Sequential studies of sleep disturbance and quality of life in abstaining alcoholics
Sequential studies of sleep disturbance and quality of life in abstaining alcoholics
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DOI：
10.1080/13556210310001646439
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发表时间：
2003-12-01
影响因子：
3.4
通讯作者：
Peters, TJ
中科院分区：
文献类型：
--
作者：
Cohn, TJ;Foster, JH;Peters, TJ
先前对最近戒毒的酗酒者的研究表明，酗酒者的睡眠受到严重干扰，生活质量受损。尽管已发现这种关联可以预测短期内酗酒的复发，但尚未进行连续研究来监测戒酒者睡眠质量和生活质量的显着变化。伦敦南部志愿部门 12 步酒精戒毒中心的 57 名住院患者接受了一系列评估睡眠（匹兹堡睡眠质量指数，PSQI）、生活质量（Euro-Qol）以及抑郁和焦虑（医院焦虑和抑郁量表，HADS）的问卷。在基线时进行问卷调查，持续 12 周，每月一次。在基线时，PSQI 评分显示 57 名参与者中有 52 人患有睡眠障碍。然而，这些分数与任何其他测量值都没有显着相关。除两名参与者外，所有参与者都承认至少在一个领域生活质量受损。关于后续测量，23 名 (40%) 参与者完成了研究。 12 周内，生活质量和抑郁评分显着改善，但睡眠和焦虑评分却没有显着改善。第 12 周时，平均 PSQI 评分仍高于“睡眠质量”的分界点。三个月的禁欲期间，生活质量和抑郁症有了显着改善，尽管此时受试者仍面临睡眠困难和焦虑。这些信息可以帮助规划未来的康复和治疗计划。
Previous studies in recently detoxified dependent alcoholics have shown severely disturbed sleep and impaired quality of life. Although this association has been found to predict short-term relapse to heavy drinking, no sequential studies have been conducted to monitor significant changes in sleep quality and quality of life in abstaining alcoholics. Fifty-seven inpatients at a voluntary sector 12-Step alcohol detoxification unit in South London were administered a series of questionnaires assessing sleep (Pittsburgh Sleep Quality Index, PSQI), Quality of Life (Euro-Qol) and Depression and Anxiety ( Hospital Anxiety and Depression Scales, HADS). Questionnaires were administered at baseline and for 12 weeks at monthly intervals. At baseline, PSQI scores showed that 52 of the 57 participants suffered from impaired sleep. The scores, however, did not correlate significantly with any of the other measurements. All except two participants acknowledged impaired Quality of Life in at least one area. With respect to the follow-up measurements 23 (40%) participants completed the study. Quality of life and depression scores improved significantly over a 12-week period but sleep and anxiety scores did not. At 12 weeks the mean PSQI score was still above the cut-off point for 'sleep caseness'. Quality of life and depression show a significant improvement over a 3-month period of abstinence, although at this point the subjects are still experiencing difficulties with sleep and anxiety. This information could help in the planning of future rehabilitation and treatment programmes.