The group of schizophrenias, schizoaffective psychoses, and affective disorders.
The group of schizophrenias, schizoaffective psychoses, and affective disorders.
复制标题
精神分裂症、分裂情感性精神病和情感障碍。
DOI：
10.1093/schbul/6.4.586
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发表时间：
1980
影响因子：
6.6
通讯作者：
M. Nüsperli
中科院分区：
文献类型：
--
作者：
C. Scharfetter;M. Nüsperli
对269名功能性精神病先证者（青春期精神病、紧张性精神病、偏执型精神分裂症、双相情感性精神病、单极情感性精神病和双相情感性精神病）和1,577名一级亲属进行了家族遗传学研究。精神分裂症和情感性精神病之间的诊断区别得到了证实，精神分裂症或情感性精神病先证者的一级亲属中约有10%患有与先证者相同的疾病。当精神分裂症先证者进一步按亚型诊断划分时，在紧张型、青春型和偏执型精神分裂症患者的亲属中，总体精神分裂症的发生率最高。关于亚型诊断，也有一种趋势，即在这3种亚型诊断的先证者亲属中出现同型继发病例。情感性先证者的亲属表现出功能性精神病的总体频率最高，精神分裂症和情感性精神病继发病例同样频繁。所有类型情感性精神病的先证者在其亲属中单极继发病例的发生率最高。（6参考）（PsycINFO数据库记录（c）2016阿帕，保留所有权利）
Conducted a family genetic study of 269 probands (hebephrenics, catatonics, paranoid schizophrenics, schizoaffective psychotics, unipolar affective psychotics, and bipolar affective psychotics) with functional psychosis and 1,577 1st-degree relatives. The diagnostic distinction between schizophrenia and affective psychosis was confirmed by the finding that approximately 10% of 1st-degree relatives of probands with schizophrenia or affective psychosis suffered from the same disorder as the proband. When schizophrenic probands were further divided by subtype diagnosis, the highest rate of global schizophrenia was found in relatives of catatonics, hebephrenics, and paranoid schizophrenics. With regard to subtype diagnoses, there was also a tendency toward homotypical secondary cases among relatives of probands with these 3 subtype diagnoses. The relatives of schizoaffective probands showed the highest overall frequency of functional psychosis, with schizophrenic and affective-psychotic secondary cases being equally frequent. Probands with affective psychosis of all types had the highest rate of unipolar secondary cases among their relatives.(6 ref)(PsycINFO Database Record (c) 2016 APA, all rights reserved)