A 48-YEAR CLINICAL AND EPIDEMIOLOGIC-STUDY OF KERATOCONUS
A 48-YEAR CLINICAL AND EPIDEMIOLOGIC-STUDY OF KERATOCONUS
复制标题
DOI：
10.1016/0002-9394(86)90817-2
复制
发表时间：
1986-03-01
影响因子：
4.2
通讯作者：
DYER, JA
中科院分区：
文献类型：
--
作者：
KENNEDY, RH;BOURNE, WM;DYER, JA
从1935年到1982年，明尼苏达州奥姆斯特德县共有64名居民（35名男性和29名女性）被新诊断为圆锥角膜。随着时间的推移，发病率没有明显的趋势;总体平均年发病率为每10万人2.0例。年龄组的发病率最高。性别之间的发病率没有显著差异。1982年12月31日，总患病率为每10万人口54.5人。诊断时，圆锥角膜单侧26例（41%），双侧38例（59%）。对患者的随访显示，生存率与一般人群没有显著差异。确诊后20年以上不进行角膜移植的累积生存概率大于80%。
From 1935 through 1982, keratoconus was newly diagnosed in a total of 64 residents (35 males and 29 females) of Olmsted County, Minnesota. There were no significant trends in incidence rates over time; the overall average annual rate was 2.0 per 100,000 population. The age-specific incidence rates were greatest in the younger groups. The incidence rates did not differ significantly by sex. On Dec. 31, 1982, the overall prevalence rate was 54.5 per 100,000 population. At the time of diagnosis, keratoconus was unilateral in 26 patients (41%) and bilateral in 38 patients (59%). Follow-up of the patients showed that survival did not differ significantly from that of the general population. The cumulative probability of survivorship without corneal transplantation for more than 20 years after diagnosis was greater than 80%.