Gender and the burden of disease attributable to obesity

Gender and the burden of disease attributable to obesity
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DOI:
10.2105/ajph.2005.068874
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发表时间:
2006-09-01
影响因子:
12.7
通讯作者:
Franks, Peter
Franks, Peter
中科院分区:
医学2区
文献类型:
--
作者:
Muennig, Peter;Lubetkin, Erica;Franks, Peter

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目标。我们按性别估算了美国因肥胖造成的疾病负担,并以预期寿命、质量调整预期寿命、每年损失的生命年和每年损失的质量调整生命年作为结果指标。方法。我们获得了属于以下体重指数类别的成年人的疾病负担估计值:正常体重(23 至 < 25)、超重(25 至 < 30)和肥胖(>= 30)。我们分析了 2000 年医疗支出小组调查,以获得与健康相关的生活质量评分,并分析了 1990-1992 年全国健康访谈调查,与截至 1995 年底的全国死亡指数数据相关的死亡率结果。相对于正常体重的男性和女性,超重男性和女性分别缩短了 27 万和 180 万质量调整生命年。肥胖男性和女性每年分别损失 190 万和 340 万质量调整生命年。超重和肥胖女性的大部分疾病负担源自较低的健康相关生活质量和晚年死亡率。结论。相对于男性,女性因超重和肥胖而承受着不成比例的疾病负担,这主要是因为与健康相关的生活质量存在差异。
Objectives. We estimated the burden of disease in the United States attributable to obesity by gender, with life expectancy, quality-adjusted life expectancy, years of life lost annually, and quality-adjusted life years lost annually as outcome measures.Methods. We obtained burden of disease estimates for adults falling into the following body-mass index categories: normal weight (23 to < 25), overweight (25 to < 30), and obese ( >= 30). We analyzed the 2000 Medical Expenditure Panel Survey to obtain health-related quality-of-life scores and the 1990-1992 National Health Interview Survey linked to National Death Index data through the end of 1995 for mortality.Results. Overweight men and women lost 270000 and 1.8 million quality-adjusted life years, respectively, relative to their normal-weight counterparts. Obese men and women lost 1.9 million and 3.4 million quality-adjusted life years, respectively, per year. Much of the burden of disease among overweight and obese women arose from lower health-related quality of life and late life mortality.Conclusions. Relative to men, women suffer a disproportionate burden of disease attributable to overweight and obesity, mostly because of differences in health-related quality of life.