NEW METHODS IN CHEMISTRY OF PYRIDAZONES

NEW METHODS IN CHEMISTRY OF PYRIDAZONES
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DOI:
10.1002/anie.196502921
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发表时间:
1965-01-01
影响因子:
16.6
通讯作者:
DURY, K
DURY, K
中科院分区:
化学1区
文献类型:
--
作者:
DURY, K

文献摘要

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丁炔二醇氯化合成粘氯酸的新方法促进了一系列4,5-二氯吡氮酮的合成。这些化合物的高反应性已经在几个方面得到了研究和应用。通过氯原子的置换,得到了一些具有生物活性的新类化合物。通过缩合和重排反应合成了新的杂环体系。
A new synthesis of mucochloric acid by chlorination of butynediol has facilitated the preparation of a series of 4,5‐dichoropyridazones. The high reactivity of these compounds has been investigated and applied in several ways. New classes of compounds, some with biological activity, were obtained by displacement of the chlorine atoms. New heterocyclic systems were prepared by condensation and rearrangement reactions.