Feasibility of Indirect Secondary Distribution of HIV Self-test Kits via WeChat Among Men Who Have Sex With Men: National Cross-sectional Study in China.
Feasibility of Indirect Secondary Distribution of HIV Self-test Kits via WeChat Among Men Who Have Sex With Men: National Cross-sectional Study in China.
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通过微信向男男性行为者间接二次分发艾滋病病毒自检试剂盒的可行性：中国全国横断面研究
DOI：
10.2196/28508
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发表时间：
2021-10-26
影响因子：
7.4
通讯作者：
Xu J
中科院分区：
文献类型：
--
作者：
Li S;Zhang J;Mao X;Lu T;Gao Y;Zhang W;Wang H;Chu Z;Hu Q;Jiang Y;Geng W;Shang H;Xu J
艾滋病毒自我检测（HIVST）试剂盒在主要性活跃人群中很常见。直接二次分发艾滋病毒/艾滋病检测试剂盒（DSDHK）可有效提高艾滋病毒/艾滋病检测的使用率。然而，有人担心DSDHK的各种限制，包括有限的地理范围，支付问题，以及需要面对面的互动。在这项研究中，我们的目的是评估通过微信间接二次分发艾滋病病毒检测试剂盒（ISDHK）的可行性和特点（分发艾滋病病毒检测申请链接和后续艾滋病病毒检测试剂盒给合作伙伴）的男性同性恋（MSM）。2017年10月至2019年9月，在微信社交媒体平台上发布了一则艾滋病毒/艾滋病检测招募广告，邀请男男性行为者申请艾滋病毒/艾滋病检测试剂盒（简称指数参与者[IP]）。鼓励所有MSM参与者通过他们的社交网络向他们的朋友和性伴侣（称为改变）分发HIVST应用程序链接。进一步鼓励所有的修改者继续分发HIVST应用程序链接。所有参与者都支付了存款（7美元），在完成调查问卷后可退还，并通过基于网络的调查系统上传测试结果。共有2263名男男性接触者符合标准并成功申请了艾滋病病毒检测。其中，1816名参与者返回了他们的HIVST结果，包括1422名（88.3%）IP和394名（21.7%）改变。更多的改变无避孕套肛交，他们中的一个较高的比例从来没有测试过艾滋病毒，他们表现出更大的意愿，分发艾滋病毒检测试剂盒给他们的性伴侣（P= 0.002）比IP。在控制了年龄、教育程度和收入之后，这些改变者中有更大比例的男男性行为者以前从未进行过艾滋病毒检测（调整后的比值比[aOR] 1.29，95%CI 1.00-1.68），更愿意分发HIVST申请链接（aOR 1.71，95% CI 1.21-2.40），性伴侣数量较少（aOR 0.71，95% CI 0.57-0.90），并且不太可能在网络上搜索性伴侣（aOR 0.78，95% CI 0.60-1.02）。相比之下，反应性HIVST结果的发生率、进行HIV确证性检测、HIV血清阳性和启动HIV抗逆转录病毒治疗的发生率在IP和变更中相似。ISDHK通过社交媒体在MSM人群中分发HIVST应用链接的模式是可行的。应采用香港爱滋病服务社的模式，以补充香港爱滋病服务社的模式，让更多男男性接触者知道他们的爱滋病病毒感染情况。
HIV self-testing (HIVST) kits are common in key sexually active populations. Direct secondary distribution of HIVST kits (DSDHK) is effective in improving the uptake of HIVST. However, there are concerns about the various limitations of DSDHK, including limited geographic reach, payment problems, and need for face-to-face interactions. In this study, we aim to evaluate the feasibility and characteristics of indirect secondary distribution of HIVST kits (ISDHK) via WeChat (distributing HIVST application links and follow-up HIVST kits to partners) among men who have sex with men (MSM). From October 2017 to September 2019, an HIVST recruitment advertisement was disseminated on the WeChat social media platform to invite MSM to apply for the HIVST kits (referred to as index participants [IPs]). All MSM participants were encouraged to distribute the HIVST application link to their friends and sexual partners (referred to as alters) through their social networks. All the alters were further encouraged to continue distributing the HIVST application link. All participants paid a deposit (US $7), which was refundable upon completion of the questionnaire, and uploaded the test results via a web-based survey system. A total of 2263 MSM met the criteria and successfully applied for HIVST. Of these, 1816 participants returned their HIVST results, including 1422 (88.3%) IPs and 394 (21.7%) alters. More alters had condomless anal intercourse, a higher proportion of them had never previously tested for HIV, and they showed a greater willingness to distribute HIVST kits to their sexual partners (P=.002) than the IPs. After controlling for age, education, and income, the alters had a greater proportion of MSM who had never tested for HIV before (adjusted odds ratio [aOR] 1.29, 95% CI 1.00-1.68), were more willing to distribute the HIVST application link (aOR 1.71, 95% CI 1.21-2.40), had a lower number of sexual partners (aOR 0.71, 95% CI 0.57-0.90), and were less likely to search for sexual partners on the web (aOR 0.78, 95% CI 0.60-1.02) than IPs. In comparison, the rates of reactive HIVST results, conducting HIV confirmatory tests, HIV seropositivity, and initiation of HIV antiretroviral therapy were similar for IPs and alters. The ISDHK model of distributing HIVST application links among the MSM population via social media is feasible. The ISDHK model should be used to supplement the DSDHK model to enable a greater proportion of the MSM population to know their HIV infection status.
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影响因子：
2.6
作者：
Matovu JKB;Kisa R;Buregyeya E;Chemusto H;Mugerwa S;Musoke W;Vrana CJ;Malek AM;Korte JE;Wanyenze RK
通讯作者：
Wanyenze RK
DOI：
10.1056/nejmoa1600693
发表时间：
2016-09-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Cohen MS;Chen YQ;McCauley M;Gamble T;Hosseinipour MC;Kumarasamy N;Hakim JG;Kumwenda J;Grinsztejn B;Pilotto JH;Godbole SV;Chariyalertsak S;Santos BR;Mayer KH;Hoffman IF;Eshleman SH;Piwowar-Manning E;Cottle L;Zhang XC;Makhema J;Mills LA;Panchia R;Faesen S;Eron J;Gallant J;Havlir D;Swindells S;Elharrar V;Burns D;Taha TE;Nielsen-Saines K;Celentano DD;Essex M;Hudelson SE;Redd AD;Fleming TR;HPTN 052 Study Team
通讯作者：
HPTN 052 Study Team
影响因子：
7.4
作者：
Cao B;Liu C;Durvasula M;Tang W;Pan S;Saffer AJ;Wei C;Tucker JD
通讯作者：
Tucker JD
影响因子：
15.8
作者：
Masters SH;Agot K;Obonyo B;Napierala Mavedzenge S;Maman S;Thirumurthy H
通讯作者：
Thirumurthy H
影响因子：
1.8
作者：
Freeman, Arin E.;Sullivan, Patrick;Mustanski, Brian
通讯作者：
Mustanski, Brian