Congenital malaria: An African survey

Congenital malaria: An African survey
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DOI:
10.1177/000992289703600706
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发表时间:
1997-07-01
影响因子:
1.6
通讯作者:
Fischer, PR
Fischer, PR
中科院分区:
医学4区
文献类型:
--
作者:
Fischer, PR

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即使在疟疾流行地区,先天性疟疾也被认为是罕见的,然而,最近的一些报告表明,在某些地区,多达四分之一的新生儿可能是寄生虫血症。为了确定目前先天性疟疾的流行率,在撒哈拉以南非洲的七个地点对100名围产期母亲的外周血和她们后代的脐带血进行了疟疾涂片检查。产妇寄生虫血症的患病率为15%的整体和不同的网站从4%到30%不等。7%的新生儿发现先天性疟疾感染,不同地点的患病率从0%到23%不等。采样季节与寄生虫血症的患病率或疟疾从母亲传给后代的传播率之间没有明显的关系。总之,先天性疟疾感染在撒哈拉以南非洲并不罕见,但新生儿寄生虫血症的患病率因地点而异。
Even in malaria-endemic areas, congenital malaria has been considered to be rare, Some recent reports suggest, however, that up to one fourth of newborns in some areas may be parasitemic. In an effort to determine current prevalence rates of congenital malaria, malaria smears were done on peripheral blood from 100 peripartum mothers and on cord blood from their offspring at each of seven sites spanning sub-Saharan Africa. The prevalence rate of maternal parasitemia was 15% overall and varied from 4% to 30% at the different sites. Congenital malarial infection was found in 7% of newborns, the prevalence rate varying from 0% to 23% at the different sites. There was no apparent relationship between the season of sampling and either the prevalence rates of parasitemia or the penetrance of malaria from mother to offspring, In summary, congenital malarial infection is not rare in sub-Saharan Africa, but the prevalence rate of neonatal parasitemia varies from site to site.