Cutaneous leishmaniasis in primary school children in the south-eastern Iranian city of Bam, 1994-95.
Cutaneous leishmaniasis in primary school children in the south-eastern Iranian city of Bam, 1994-95.
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1994-95 年，伊朗东南部城市巴姆小学生患皮肤利什曼病。
DOI：
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发表时间：
1998
影响因子：
11.1
通讯作者：
A. Kamesipour
中科院分区：
文献类型：
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作者：
I. Sharifi;A. Fekri;M. Aflatonian;A. Nadim;Y. Nikian;A. Kamesipour
1994年8月至1995年7月，对伊朗东南部城市巴姆市的11517名6-11岁小学生进行了皮肤利什曼病活动性损害或疤痕检查，其中5560名(48.3%)女孩和5957名(51.7%)男孩。患病率有随年龄增长的趋势，6岁儿童患病率为10.7%，11岁儿童患病率为20%。总体而言，1.3%的儿童有活跃的皮损，14.3%的儿童有疤痕。活动性皮损和/或瘢痕的患病率在性别间无显著差异。在接受检查的儿童中，54名(0.5%)有反复利什曼病：女孩19名(35.2%)，男孩35名(64.8%)。活动性皮损或瘢痕数目为1~10个。大多数(82.3%)有1个皮损，12.4%有2个皮损，5.3%有3个，平均1.08个(女孩1.03个，男孩1.18个)。面部是受累最多的部位(63.6%)，其次是手(20.9%)、腿(12.8%)和身体其他部位(2.7%)。对14例儿童分离的病原菌进行检测，13例(92.9%)为热带利什曼原虫，另1例(7.1%)为大型利什曼原虫。调查表明，CL的地理分布比人们之前认为的要广泛得多。它还表明，巴姆是适合进行疫苗现场试验的地区。
Between August 1994 and July 1995, 11,517 primary school children aged 6-11 years in the south-eastern Iranian city of Bam, comprising 5560 (48.3%) girls and 5957 (51.7%) boys, were examined for the presence of active lesions or scars of cutaneous leishmaniasis (CL). There was a trend towards increasing prevalence with age, the prevalence being 10.7% in 6-year-old and 20% in > or = 11-year-old children. Overall, 1.3% of the children had active lesions and 14.3% had scars. There was no significant difference between the sexes in the prevalence of active lesions and/or scars. Of the children examined, 54 (0.5%) had leishmaniasis recidivans: 19 girls (35.2%) and 35 boys (64.8%). The number of active lesions or scars per child ranged from 1 to 10. The majority (82.3%) had 1 lesion, 12.4% had 2 lesions, and 5.3% had > or = 3. The average number of lesions was 1.08 (1.03 in girls and 1.18 in boys). The face was the part of the body most commonly involved (63.6%), followed by the hands (20.9%), legs (12.8%) and other parts of the body (2.7%). Examination of isolates from 14 children revealed that in 13 (92.9%) the causal organism was Leishmania tropica and in the other (7.1%) L. major. The survey indicates that the geographical distribution of CL is far wider than previously thought. It also shows that Bam is a suitable areas for a vaccine field trial.