Expression of plasmid DNA released from DNA conjugates of gold nanorods

Expression of plasmid DNA released from DNA conjugates of gold nanorods
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DOI:
10.1246/cl.2007.952
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发表时间:
2007-07-05
期刊:
影响因子:
1.6
通讯作者:
Niidome, Yasuro
Niidome, Yasuro
中科院分区:
化学4区
文献类型:
--
作者:
Horiguchi, Yukichi;Niidome, Takuro;Niidome, Yasuro

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脉冲激光照射诱导DNA与金纳米棒(GNRs)偶联物释放质粒DNA。凝胶电泳结果表明,与GNRs结合的质粒DNA有1%被释放。体外实验表明,0.5%的质粒DNA有活性。
Pulsed-laser irradiation induced the release of plasmid DNA from conjugates of DNA and gold nanorods (GNRs). Gel electrophoresis indicated that 1% of the plasmid DNA conjugated with GNRs was released from the conjugates. In vitro assay indicated that 0.5% of plasmid DNA was active.