Maternal anxiety disorders predict excessive infant crying: a prospective longitudinal study
Maternal anxiety disorders predict excessive infant crying: a prospective longitudinal study
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DOI：
10.1136/archdischild-2013-305562
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发表时间：
2014-09-01
影响因子：
5.2
通讯作者：
Martini, Julia
中科院分区：
文献类型：
--
作者：
Petzoldt, Johanna;Wittchen, Hans-Ulrich;Martini, Julia
目的 前瞻性探讨母亲 DSM-IV-TR 焦虑和抑郁障碍与婴儿过度哭泣之间的关系。方法基于前瞻性纵向母亲焦虑与婴儿发育关系研究，纳入 306 名妊娠早期孕妇，并重复访谈直至产后 16 个月。通过标准化诊断访谈（女性综合国际诊断访谈）评估了有关母亲焦虑和抑郁症的终生和前瞻性信息。通过 Baby-DIPS 评估过度哭泣（每周哭泣 ≥ 3 天，每天哭泣 >= 3 小时）。在分娩后的前 16 个月内，n=286 名母婴二人组可用并纳入分析。结果 n=29 名母亲 (10.1%) 报告过度哭泣。怀孕前患有焦虑症的母亲的婴儿比怀孕前没有任何焦虑症的母亲的婴儿过度哭泣的风险更高（OR = 2.54，95％CI 1.11至5.78，p = 0.027）。如果额外考虑到分娩前（OR=3.02，95% CI 1.25至7.32，p=0.014）和产后16个月（OR=2.87，95% CI 1.13至7.28，p=0.027）发生焦虑症，风险甚至会增加。在调整社会人口统计学和围产期协变量后，关联保持稳定。在该样本中，怀孕前的母亲抑郁症与过度哭泣没有显着相关性。 意义 母亲的一生和发生的焦虑症被证明是过度哭泣的有力预测因素。因此，早期识别和监测患有焦虑症的女性对于识别有过度哭泣风险的母婴二人非常重要。
Purpose To prospectively examine relations between maternal DSM-IV-TR anxiety and depressive disorders and excessive infant crying.Methods Based on the prospective longitudinal Maternal Anxiety in Relation to Infant Development Study, n=306 expectant mothers were enrolled during early pregnancy and repeatedly interviewed until 16 months post partum. Lifetime and prospective information on maternal anxiety and depressive disorders was assessed via standardised diagnostic interviews (Composite International Diagnostic Interview for Women). Excessive crying (crying for >= 3 h per day on >= 3 days per week for >= 3 weeks) was assessed via Baby-DIPS. During the first 16 months after delivery, n=286 mother-infant dyads were available and included in the analyses.Results Excessive crying was reported by n=29 mothers (10.1%). Infants of mothers with anxiety disorders prior to pregnancy were at higher risk for excessive crying than infants of mothers without any anxiety disorder prior to pregnancy (OR=2.54, 95% CI 1.11 to 5.78, p=0.027). Risk was even increased when considering additionally incident anxiety disorders until delivery (OR=3.02, 95% CI 1.25 to 7.32, p=0.014) and until 16 months post partum (OR=2.87, 95% CI 1.13 to 7.28, p=0.027). Associations remained stable when adjusting for sociodemographic and perinatal covariates. Maternal depressive disorders prior to pregnancy were not significantly associated with excessive crying in this sample.Implications Maternal lifetime and incident anxiety disorders revealed to be a robust predictor for excessive crying. Thus, early identification and monitoring of women with anxiety disorders is important to identify mother-infant dyads at risk for excessive crying.