Analysis of green algal growth via dynamic model simulation and process optimization
Analysis of green algal growth via dynamic model simulation and process optimization
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通过动态模型模拟和过程优化分析绿藻生长
DOI：
10.1002/bit.25610
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发表时间：
2015
影响因子：
3.8
通讯作者：
B. Tamburic
中科院分区：
文献类型：
--
作者：
Dongda Zhang;E. A. D. Chanona;V. Vassiliadis;B. Tamburic
莱茵衣藻是一种绿色微藻，具有为未来生产可持续生物燃料的潜力。需要过程模拟模型来预测实验室规模生长实验对未来规模系统运行的影响。建立了两种动态模型来模拟莱茵哈德菌的光自养和光混合营养生长。采用一种新的参数估计方法确定了两种模型中关键参数的取值，并用实验结果对其进行了验证。采用光混合营养模型准确预测了不同光强和不同光生物反应器配置下莱茵梭菌的生长情况。结果表明，藻体光自养生长的最佳CO2浓度为0.0643 g·L−1，光强为47 W·m−2。敏感性分析表明，在不同的生长方式下，限制青松生长的主要因素是其固有的细胞衰减率，而不是光衰减。光混合营养生长模型也被用于预测不同平板光生物反应器规模下的最大生物量浓度。较低光强（小于50 W·m−2）的双曝光表面光生物反应器是按比例培养莱茵哈德梭菌的最佳配置。模拟和优化了三种不同的短期（30天）莱茵哈蒂草光混合营养培养过程。在连续光生物反应器运行条件下，最大生物量生产力为0.053 g·L−1·hr−1。连续搅拌槽反应器是最佳的运行模式，因为它提供了最高的生物质生产率和最低的泵运行电力成本。Biotechnol。Bioeng。2015;112: 2025 - 2039。©2015 Wiley期刊公司
Chlamydomonas reinhardtii is a green microalga with the potential to generate sustainable biofuels for the future. Process simulation models are required to predict the impact of laboratory‐scale growth experiments on future scaled‐up system operation. Two dynamic models were constructed to simulate C. reinhardtii photo‐autotrophic and photo‐mixotrophic growth. A novel parameter estimation methodology was applied to determine the values of key parameters in both models, which were then verified using experimental results. The photo‐mixotrophic model was used to accurately predict C. reinhardtii growth under different light intensities and in different photobioreactor configurations. The optimal dissolved CO2 concentration for C. reinhardtii photo‐autotrophic growth was determined to be 0.0643 g·L−1, and the optimal light intensity for algal growth was 47 W·m−2. Sensitivity analysis revealed that the primary factor limiting C. reinhardtii growth was its intrinsic cell decay rate rather than light attenuation, regardless of the growth mode. The photo‐mixotrophic growth model was also applied to predict the maximum biomass concentration at different flat‐plate photobioreactors scales. A double‐exposure‐surface photobioreactor with a lower light intensity (less than 50 W·m−2) was the best configuration for scaled‐up C. reinhardtii cultivation. Three different short‐term (30‐day) C. reinhardtii photo‐mixotrophic cultivation processes were simulated and optimised. The maximum biomass productivity was 0.053 g·L−1·hr−1, achieved under continuous photobioreactor operation. The continuous stirred‐tank reactor was the best operating mode, as it provides both the highest biomass productivity and lowest electricity cost of pump operation. Biotechnol. Bioeng. 2015;112: 2025–2039. © 2015 Wiley Periodicals, Inc.
影响因子：
4.9
作者：
Kosourov, S;Seibert, M;Ghirardi, ML
通讯作者：
Ghirardi, ML