Atherosclerosis in the mouse
Atherosclerosis in the mouse
复制标题
小鼠动脉粥样硬化
DOI：
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复制
发表时间：
1989
期刊：
影响因子：
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通讯作者：
B. Paigen
中科院分区：
文献类型：
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作者：
B. Ishida;B. Paigen
然而，只是在最近几年，已经开发出适当的实验方案，可靠地在小鼠中产生可重复的动脉粥样硬化病变。本综述将总结这些方案的特点，在小鼠中可用的遗传工具，到目前为止已确定的脂质转运和动脉粥样硬化易感性的基因，以及小鼠的脂蛋白谱
Only in recent years, however, have appropriate experimental regimens been developed that reliably result in reproducible atherosclerotic lesions in the mouse. This review will summarize the characteristics of these regimens, the genetic tools available in the mouse, the genes in lipid transport and atherosclerosis susceptibility that have so far been identified, and the lipoprotein profile of the mouse