Altered Neurometabolic Profile in Early Parkinson's Disease: A Study With Short Echo-Time Whole Brain MR Spectroscopic Imaging
Altered Neurometabolic Profile in Early Parkinson's Disease: A Study With Short Echo-Time Whole Brain MR Spectroscopic Imaging
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DOI：
10.3389/fneur.2019.00777
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发表时间：
2019-07-17
影响因子：
3.4
通讯作者：
Ding, Xiao-Qi
中科院分区：
文献类型：
--
作者：
Klietz, Martin;Bronzlik, Paul;Ding, Xiao-Qi
目的：应用短回声时间全脑磁共振波谱成像(WbMRSI)作为早期诊断和监测帕金森病(PD)的可能生物标志物，评价早期帕金森病(PD)患者的神经代谢变化。
Objective: To estimate alterations in neurometabolic profile of patients with early stage Parkinson's disease (PD) by using a short echo-time whole brain magnetic resonance spectroscopic imaging (wbMRSI) as possible biomarker for early diagnosis and monitoring of PD.Methods: 20 PD patients in early stage (H&Y