Occupations associated with COPD risk in the large population-based UK Biobank cohort study
Occupations associated with COPD risk in the large population-based UK Biobank cohort study
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DOI：
10.1136/oemed-2015-103406
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发表时间：
2016-06-01
影响因子：
4.9
通讯作者：
Cullinan, Paul
中科院分区：
文献类型：
--
作者：
De Matteis, Sara;Jarvis, Deborah;Cullinan, Paul
慢性阻塞性肺疾病（COPD）是世界范围内发病率和死亡率的主要原因。暴露于职业危害是一个重要的可预防的风险因素，但在一般人群中，特定职业对COPD风险的贡献是不确定的。我们的目的是调查英国人群中COPD与职业的关系。方法2006-2010年，英国生物银行队列招募了502649名年龄在40-69岁之间的成年人。COPD病例以支气管扩张剂前用力呼气量1 s/用力肺活量鉴别
Objectives Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Exposure to occupational hazards is an important preventable risk factor but the contribution of specific occupations to COPD risk in a general population is uncertain. Our aim was to investigate the association of COPD with occupation in the UK population.Methods In 2006-2010, the UK Biobank cohort recruited 502 649 adults aged 40-69 years. COPD cases were identified by prebronchodilator forced expiratory volume in 1 s/forced vital capacity