Case study: Folate bioavailability

Case study: Folate bioavailability
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DOI:
10.1093/jn/131.4.1376s
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发表时间:
2001-04-01
影响因子:
4.2
通讯作者:
Gregory, JF
Gregory, JF
中科院分区:
医学2区
文献类型:
--
作者:
Gregory, JF

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叶酸的营养状况取决于食物和补充剂的摄入量,以及这种维生素的各种摄入形式的生物利用度。尽管近年来在了解叶酸的生物利用度方面取得了许多进展。许多不确定的领域仍然存在,特别是关于天然存在的膳食叶酸。本文综述了影响叶酸吸收和利用的因素、目前使用的和有希望的生物利用度评估方法、当前认识所基于的重要发现和研究需要。
Folate nutritional status depends on intake from food and supplements as well as on the bioavailability of the various ingested forms of this vitamin. Although many advances in the understanding of folate bioavailability have occurred in recent years. many areas of uncertainty remain, especially with respect to naturally occurring dietary folate. This review includes a summary of factors that affect folate absorption and utilization, currently used and promising methods suitable for the assessment of bioavailability, significant findings on which current understanding is based and research needs.