Effect of Contrast on Visual Spatial Summation in Different Cell Categories in Cat Primary Visual Cortex.
Effect of Contrast on Visual Spatial Summation in Different Cell Categories in Cat Primary Visual Cortex.
复制标题
对比度对猫初级视觉皮层不同细胞类别视觉空间总和的影响
DOI：
10.1371/journal.pone.0144403
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Song XM
中科院分区：
文献类型：
--
作者：
Chen K;Ding AM;Liang XH;Zhang LP;Wang L;Song XM
在初级视皮层中已经发现了多种细胞类型，但很少有人研究细胞类型与空间总和之间的关系。小白蛋白表达的抑制性中间神经元可以根据其较短的动作电位时程与锥体神经元区分开来。在这项研究中，我们将V1细胞分为快峰单位(FSU)和规则峰单位(RSU)，然后检查高对比度和低对比度下的空间总和。结果表明，FSU和RSU的兴奋性经典感受野和抑制性非经典感受野均以低对比度扩展，但RSU的扩展比FSU更明显。对于大多数V1神经元，环绕抑制随着对比度从高到低的变化而变化。然而，FSU在高对比度和低对比度之间的抑制强度没有显著差异，尽管在低对比度下RSU的总体抑制显著降低。我们的结果表明，刺激对比度对空间总和的调制在猫初级视觉皮质的不同神经元群体中是不同的。
Multiple cell classes have been found in the primary visual cortex, but the relationship between cell types and spatial summation has seldom been studied. Parvalbumin-expressing inhibitory interneurons can be distinguished from pyramidal neurons based on their briefer action potential durations. In this study, we classified V1 cells into fast-spiking units (FSUs) and regular-spiking units (RSUs) and then examined spatial summation at high and low contrast. Our results revealed that the excitatory classical receptive field and the suppressive non-classical receptive field expanded at low contrast for both FSUs and RSUs, but the expansion was more marked for the RSUs than for the FSUs. For most V1 neurons, surround suppression varied as the contrast changed from high to low. However, FSUs exhibited no significant difference in the strength of suppression between high and low contrast, although the overall suppression decreased significantly at low contrast for the RSUs. Our results suggest that the modulation of spatial summation by stimulus contrast differs across populations of neurons in the cat primary visual cortex.