Cloninger's temperament and character dimensions of personality in patients with major depressive disorder

Cloninger's temperament and character dimensions of personality in patients with major depressive disorder
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DOI:
10.1016/j.comppsych.2008.11.012
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发表时间:
2009-11-01
影响因子:
7.3
通讯作者:
Cloninger, C. Robert
Cloninger, C. Robert
中科院分区:
医学2区
文献类型:
--
作者:
Celikel, Feryal Cam;Kose, Samet;Cloninger, C. Robert

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在本研究中,我们探讨了Cloninger的人格和抑郁症的门诊人群的维度心理生物学模型之间的关系与重性抑郁症。81名抑郁症门诊患者(67名女性,14名男性)和51名健康对照(35名女性,16名男性)填写了土耳其版的气质和性格量表(TCI)。采用17项汉密尔顿抑郁量表和21项贝克抑郁量表评估抑郁严重程度。与健康对照组相比,抑郁症患者在避免伤害方面表现出统计学显著性较高的得分,在自我导向方面表现出统计学显著性较低的得分。抑郁组的情感性(RD 1)和依赖性(RD 4)、自我超越的精神接受(ST 3)分显著高于对照组,依恋性(RD 3)、责任性(SDI)、目的性(SD 2)、机智性(SD 3)和一致性第二天性(SD 5)分显著低于对照组。在抑郁症患者组中,性别对奖励依赖和合作性的主效应显著;女性在这两个维度上的得分较高,贝克量表与伤害回避呈正相关,与新奇寻求和自我导向维度呈负相关(P < .05)。抑郁症的持续时间(16.33 ± 20.18个月)或抑郁症的平均发病年龄(28.68 ± 8.11岁)与TCI量表无显著相关性。本研究证实了伤害回避与抑郁之间的关系,并提出了自我导向与抑郁之间的关系。(C)2009 Elsevier Inc. All rights reserved.
In this present study, we examined the relationship between the Cloninger's dimensional psychobiologic model of personality and depression in an outpatient population with major depressive disorder. Eighty-one depressed Outpatients (67 women, 14 men) and 51 healthy controls (35 women, 16 men) filled out the Turkish version of the Temperament and Character Inventory (TCI). Depression severity was evaluated by using the 17-item Hamilton Depression Rating Scale and the 21-item Beck Depression Inventory. Depressed patients exhibited statistically significant higher scores for harm avoidance and lower scores for self-directedness compared to healthy controls. Sentimentality (RD1) and dependence (RD4) subscale scores of reward dependence and spiritual acceptance (ST3) subscale of self-transcendence were significantly higher; attachment (RD3) subscale of reward dependence, responsibility (SDI), purposefulness (SD2), resourcefulness (SD3), and congruent second nature (SD5) subscales of self-directedness were significantly lower in the depressed group. In the depressed patient group, main effects of sex were significant for reward dependence and cooperativeness; the scores of both dimensions were higher for women, The Beck Inventory was positively correlated with harm avoidance and negatively correlated with novelty seeking and self-directedness dimensions (P < .05). The duration of depression (16.33 +/- 20.18 months) or the mean onset age of depression (28.68 +/- 8.11 years) did not show significant correlations with TCI scales. This study confirms the relationship between harm avoidance and depression and Suggests a relationship between self-directedness and depression. (C) 2009 Elsevier Inc. All rights reserved.