Cases in Precision Medicine: Is There an Obligation to Return Reinterpreted Genetic Results to Former Patients?
Cases in Precision Medicine: Is There an Obligation to Return Reinterpreted Genetic Results to Former Patients?
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DOI：
10.7326/m22-3682
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发表时间：
2023-04
影响因子：
39.2
通讯作者：
Chung WK
中科院分区：
文献类型：
--
作者：
Appelbaum PS;Burke W;Parens E;Roberts J;Berger SM;Chung WK
随着新数据的积累，许多基因检测结果的解释可能会随着时间的推移而改变。因此，进行基因检测的医生可能随后会收到对患者的医学治疗有重要影响的修订报告，甚至对那些不再接受他们治疗的患者也是如此。医疗实践中的一些伦理原则表明，有义务向以前的病人提供这些信息。履行这一义务可以完成，至少，通过尝试联系前病人与他们的最后一个已知的联系信息。
Interpretation of many genetic test results can change over time as new data accumulate. Hence, physicians who order genetic tests may subsequently receive revised reports with important implications for patients’ medical treatment—even for patients who are no longer in their care. Several of the ethical principles underlying medical practice suggest an obligation to reach out to former patients with this information. Discharging that obligation can be accomplished, at a minimum, by attempting to contact the former patient with their last known contact information.