CONTACT SPACING AMONG ASTROCYTES IN THE CENTRAL-NERVOUS-SYSTEM - AN HYPOTHESIS OF THEIR STRUCTURAL ROLE
CONTACT SPACING AMONG ASTROCYTES IN THE CENTRAL-NERVOUS-SYSTEM - AN HYPOTHESIS OF THEIR STRUCTURAL ROLE
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DOI：
10.1002/glia.440040508
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发表时间：
1991-01-01
期刊：
影响因子：
6.2
通讯作者：
STONE, J
中科院分区：
文献类型：
--
作者：
DISTLER, C;DREHER, Z;STONE, J
星形胶质细胞遍布中枢神经系统。它们与周围结构密切相互作用，其过程有助于神经管的神经胶质限制，血管的神经胶质投资，以及神经元的体细胞，轴突和突触结构。本文提出的证据表明，中枢神经系统中的星形胶质细胞也以双重方式相互作用，通过其过程粘附其邻居，并排斥这些邻居的体细胞。我们认为这种相互作用，被称为接触间隔，通过中枢神经系统分布星形胶质细胞，并形成其结构作用的基础。
Astrocytes are found throughout the central nervous system. They interact closely with surrounding structures, their processes contributing to the glia limitans of the neural tube, and to the glial investment of blood vessels, and of the somas, axons, and synaptic structures of neurones. This paper presents evidence that astrocytes in the central nervous system also interact with each other in a dual way, adhering to their neighbours via their processes, and repelling the somas of those neighbours. We suggest that this interaction, which has been termed contact spacing, distributes astrocytes through the central nervous system, and forms the basis of their structural role.