Normal organ volume assessment from abdominal CT
Normal organ volume assessment from abdominal CT
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DOI：
10.1007/s00261-003-0139-2
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发表时间：
2004-07-01
影响因子：
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通讯作者：
Jain, K
中科院分区：
文献类型：
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作者：
Geraghty, EM;Boone, JM;Jain, K
我们根据腹部计算机断层扫描(CT)图像确定腹部器官体积的正态分布。共选择149例成人腹部CT检查，用计算机在每张CT图像上手工勾画出711个器官(男性388个，女性323个)。研究人员追踪了18,000多个器官轮廓。研究的器官包括左肾和右肾、左右肾上腺、脾、胰腺和肝脏，并对第一腰椎进行了评估。使用已知的像素大小和切片厚度，计算器官体积。器官体积根据性别的身高和体重进行了校正。计算了所研究的每个器官的正态分布和累积正态分布，显示了正常成年人群中存在的每个性别的器官体积范围。器官体积从平均4.4ml(女性左肾上腺)到1710mL(男性肝脏)不等。雌性胰腺、肾脏、脾和肝脏的平均器官体积分别为64.4mL、156.5、179.8和1411mL。相应的雄性体积分别为87.4m L、193.1 m L、238.4 m L和1710m L。提供表格数据，根据累积概率分布指示每个器官体积的相对大小。提供的标准数据使医生能够估计特定器官体积在正常范围内的位置。器官体积可作为病理状态的定量指标。
We determined the normal distribution of abdominal organ volumes measured from abdominal computed tomographic (CT) images. A total of 149 adult abdominal CT studies were selected, and 711 organs (388 from males, 323 from females) were outlined by hand on each CT image by using a computer. More than 18,000 organ outlines were traced. The organs studied included left and right kidneys, left and right adrenals, spleen, pancreas, and liver, and the first lumbar vertebrae was also evaluated. Using the known pixel size and section thickness, organ volumes were computed. Organ volumes were corrected for height and weight for each sex. The normal and cumulative normal distributions for each organ studied were computed, demonstrating the range of organ volumes for each sex that exist in the normal adult population. Organ volumes ranged from a mean of 4.4 mL (female left adrenal) to 1710 mL (male liver). Mean organ volumes were 64.4, 156.5, 179.8, and 1411 mL for the female pancreas, kidneys, spleen, and liver, respectively. Corresponding male volumes were 87.4, 193.1, 238.4, and 1710 mL, respectively. Tabular data are provided that indicate the relative size for each organ volume in terms of the cumulative probability distribution. Normative data are provided to allow physicians to estimate where in the normal range a particular organ volume lays. Organ volumes may be useful as quantitative indices of pathologic conditions.