Presymptomatic Transmission of SARS-CoV-2-Singapore, January 23-March 16, 2020
Presymptomatic Transmission of SARS-CoV-2-Singapore, January 23-March 16, 2020
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DOI：
10.15585/mmwr.mm6914e1
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发表时间：
2020-04-10
影响因子：
33.9
通讯作者：
Lee, Vernon J.
中科院分区：
文献类型：
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作者：
Wei, Wycliffe E.;Li, Zongbin;Lee, Vernon J.
关于这个话题已经知道什么？根据中国个别病例的报告，初步证据表明 SARS-CoV-2 出现症状前传播。本报告补充了哪些内容？对 1 月 23 日至 3 月 16 日期间新加坡报告的所有 243 例 COVID-19 病例进行调查，发现了七组病例，其中症状前传播是继发病例发生最有可能的解释。对公共卫生实践有什么影响？症状前传播的可能性传播增加了遏制措施的挑战。进行接触者追踪的公共卫生官员应强烈考虑纳入症状出现前的一段时间，以考虑症状前传播的可能性。症状前传播的可能性凸显了保持社交距离（包括避免聚集场所）对于减少 COVID-19 传播的重要性。
What is already known about this topic?Preliminary evidence indicates the occurrence of presymptomatic transmission of SARS-CoV-2, based on reports of individual cases in China.What is added by this report?Investigation of all 243 cases of COVID-19 reported in Singapore during January 23-March 16 identified seven clusters of cases in which presymptomatic transmission is the most likely explanation for the occurrence of secondary cases.What are the implications for public health practice?The possibility of presymptomatic transmission increases the challenges of containment measures. Public health officials conducting contact tracing should strongly consider including a period before symptom onset to account for the possibility of presymptomatic transmission. The potential for presymptomatic transmission underscores the importance of social distancing, including the avoidance of congregate settings, to reduce COVID-19 spread.