A computational study of lateral phase separation in biological membranes
A computational study of lateral phase separation in biological membranes
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DOI：
10.1002/cnm.3181
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发表时间：
2018-08
影响因子：
2.1
通讯作者：
V. Yushutin;A. Quaini;Sheereen Majd;M. Olshanskii
中科院分区：
文献类型：
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作者：
V. Yushutin;A. Quaini;Sheereen Majd;M. Olshanskii
保守和非保守相场模型被考虑用于生物膜横向相分离和粗化的数值模拟。提出了一种不拟合的有限元方法，可以在没有显式表面参数化的情况下灵活处理复杂形状。对于一组生物学相关的形状和参数值，本文比较了保守和非保守数值模型产生的动态粗化、其对某些几何特征的依赖以及对最终平衡的收敛。
Conservative and non‐conservative phase‐field models are considered for the numerical simulation of lateral phase separation and coarsening in biological membranes. An unfitted finite element method is proposed to allow for a flexible treatment of complex shapes in the absence of an explicit surface parametrization. For a set of biologically relevant shapes and parameter values, the paper compares the dynamic coarsening produced by conservative and non‐conservative numerical models, its dependence on certain geometric characteristics and convergence to the final equilibrium.