Cytogenetic study of malignant histiocytosis transplanted into nude mice; presence of translocation between chromosomes 5 and 6 and a unique marker (13q+)
Cytogenetic study of malignant histiocytosis transplanted into nude mice; presence of translocation between chromosomes 5 and 6 and a unique marker (13q+)
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恶性组织细胞增多症裸鼠移植的细胞遗传学研究
DOI：
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
C. Nezelof
中科院分区：
文献类型：
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作者：
J. Soulié;M. Rousseau;H. Mouly;C. Nezelof
将一例恶性组织细胞增生症患儿的胸腔积液中的液体移植到裸鼠体内。对异种移植细胞进行细胞遗传学研究，结果显示具有易位t（5; 6）和标记（13 q+）的二倍体核型。这项研究报告了恶性组织细胞增生症中一种新的重排，此前尚未描述过。
SummaryFluid from a pleural effusion in a child with malignant histiocytosis was grafted into nude mice. Cytogenetic studies were performed on the xenografted cells which revealed a diploid karyotype with a translocation t (5; 6) and a marker (13q +). This study reports a new rearrangement which has not been described previously in malignant histiocytosis.
高分辨率染色体作为成人急性非淋巴细胞白血病的独立预后指标。
DOI：
10.1056/nejm198409273111302
发表时间：
1984
期刊：
The New England journal of medicine
影响因子：
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作者：
Yunis,JJ;Brunning,RD;Howe,RB;Lobell,M
通讯作者：
Lobell,M