Bone-supportive behavior of microplasma-sprayed CaP-coated implants: mechanical and histological outcome in the goat
Bone-supportive behavior of microplasma-sprayed CaP-coated implants: mechanical and histological outcome in the goat
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DOI：
10.1111/j.1600-0501.2009.01819.x
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发表时间：
2010-02-01
影响因子：
4.3
通讯作者：
Jansen, J. A.
中科院分区：
文献类型：
--
作者：
Junker, R.;Manders, P. J. D.;Jansen, J. A.
背景研究开发了一种新型微束等离子喷涂（MPS）设备，用于在钛基体上制备存款磷酸钙（CaP）陶瓷涂层。使用该设备，可以喷涂细颗粒，以及将纹理化的羟基磷灰石涂层施加到钛表面上。此外，由于微等离子体射流的低热功率，减少了粉末颗粒的过热以及基底的过度局部过热。此外，由于小的层流等离子体射流，在喷涂牙科植入物的情况下可以实现高喷涂效率。此外，低噪音（25-50 dB）并且几乎没有任何灰尘使得可以在正常的工作室条件下操作MSE。本研究的目的是检查当插入山羊股骨髁时钛植入物上的不同MPS - CaP涂层的生物学特性。材料和方法对于组织形态计量学评价以及机械测试，将48枚螺钉型钛种植体植入12只山羊股骨髁内。植入物涂覆有常规等离子喷涂的CaP陶瓷、MPS CaP陶瓷或酸蚀刻而没有额外的CaP涂层。植入后6周和12周，动物被处死，骨-种植体接触，骨的量，以及机械骨固定进行了evaluated.ResultsFor骨-种植体接触没有统计学显着差异，发现不同的钙磷涂层之间。然而，在6周和12周愈合后，发现无涂层酸蚀钛种植体和CaP涂层种植体之间存在统计学显著差异。在6周和12周时，不同CaP涂层之间的骨值没有统计学显著差异。此外，在愈合6周和12周后，与无涂层种植体相比，CaP陶瓷涂层种植体的扭矩值在统计学上显著更高。各种类型的CaP coatings.ConclusionOn the basis of our observations，we concluded that conventionally plasma sprayed CaP ceramic-coated implants，as well as the MPS-coated implants have a comparable effect on adjacent bone responsibility.To cite this article：Junker R，Manders PJD，Wolke J，Borisov Y，Jansen JA.微等离子喷涂钙磷涂层种植体的骨支持行为：山羊的机械和组织学结果。Res. 21，2010; 189-200.doi：10.1111/j.1600-0501.2009.01819.x.
BackgroundNew microplasma spray (MPS) equipment to deposit calcium phosphate (CaP) ceramic coatings onto titanium substrates has been developed. With this apparatus, it is possible to spray fine particles, as well as to apply textured hydroxylapatite coatings onto titanium surfaces. Moreover, due to the low heat power of the microplasma jet, overheating of the powder particles as well as excessive local overheating of the substrate is reduced. Furthermore, because of the small laminar plasma jet, it is possible to achieve high spray efficiency in the case of spraying of dental implants. Additionally, the low level of noise (25-50 dB) and hardly any dust makes it possible to operate the MSE under normal workroom conditions.ObjectiveThe aim of this study was to examine the biological properties of different MPS - CaP coatings on titanium implants when inserted into the femoral condyle of goats.Material and methodsFor histomorphometrical evaluation as well as mechanical testing, 48 screw-type titanium implants were inserted into the femoral condyles of 12 goats each. The implants were either coated with a conventionally plasma-sprayed CaP ceramic, MPS CaP ceramic, or acid-etched without an additional CaP coating. Six and 12 weeks after implantation, the animals were sacrificed and bone-to-implant contact, amount of bone, as well as mechanical bone fixation were evaluated.ResultsFor bone-to-implant contact no statistically significant difference was found between the different CaP coatings. However, statistically significant differences were found between non-coated, acid-etched titanium implants and CaP-coated implants after 6 and 12 weeks of healing. The bone values were not statistically significantly different between the different CaP coatings at 6 and 12 weeks. Furthermore, CaP ceramic-coated implants showed statistically significantly higher torque values compared with the non-coated implants after 6 and at 12 weeks of healing. No significant differences existed between the various types of CaP coatings.ConclusionOn the basis of our observations, we conclude that conventionally plasma-sprayed CaP ceramic-coated implants, as well as MPS-coated implants have a comparable effect on adjacent bone response.To cite this article:Junker R, Manders PJD, Wolke J, Borisov Y, Jansen JA. Bone-supportive behavior of microplasma-sprayed CaP-coated implants: mechanical and histological outcome in the goat.Clin. Oral Impl. Res. 21, 2010; 189-200.doi: 10.1111/j.1600-0501.2009.01819.x.