Use of scintigraphy to evaluate gastric accommodation and emptying: comparison with barostat.
Use of scintigraphy to evaluate gastric accommodation and emptying: comparison with barostat.
复制标题
使用闪烁扫描法评估胃的调节和排空：与恒压器的比较。
DOI：
10.1111/j.1440-1746.2012.07261.x
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Miwa H.
中科院分区：
文献类型：
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作者：
Tomita T;Okugawa T;Yamasaki T;Kondo T;Toyoshima F;Sakurai J;Oshima T;Fukui H;Daimon T;Watari J;Kashiwagi T;Matsumoto T;Miwa H.
背景和目的扫描是一种有用的无创技术来评估胃运动，特别是排空，但很少有人知道如何使用该技术来评估胃调节。因此，为了明确闪烁成像作为评估胃调节的技术的有效性，我们将闪烁成像与压力计进行了比较，后者是金标准模式。方法20例健康志愿者（男14例，女6例，平均年龄28.5±5.4岁）入组研究。志愿者摄入了放射性标记（99mTc）的测试餐，并记录了科学图像。计算上三分之一胃和全胃的放射性以评价适应性。在恒压过程中，胃调节是通过测量膨胀球囊的最大体积来评估的。然后，研究了科学测量和气压调节之间的相关性。还评估了星图试验结果的观察者内部和观察者之间的差异。最后，以舒马曲坦为阳性对照，评价闪烁显像的诊断性能。结果闪烁仪测量的适应度与气压计测量值相关（r = 0.524，P< 0.05）。舒马曲坦显著提高了经扫描测量的胃调节功能（有舒马曲坦组为51.5±16.4%，无舒马曲坦组为38.4±13.8%）（P< 0.01），并显著（P< 0.05）延迟了实验开始后60、90、120和150 min的50%半排空时间。来自重复闪烁试验的数据具有高度可重复性（r = 0.804），研究者之间未观察到显著差异（观察者间变异= 0.932，观察者内变异= 0.898）。结论胃造影是评价胃调节和排空的有效方法。
Background and AimScintigraphy is a useful noninvasive technique for assessment of gastric motility, especially emptying, but there is little knowledge of use of the technique to assess gastric accommodation. Therefore, to clarify the usefulness of scintigraphy as a technique for assessing gastric accommodation, we compared scintigraphy with barostat, the gold standard modality.MethodsTwenty healthy volunteers (14 men, six women; mean age, 28.5 ± 5.4 years) were enrolled in the study. The volunteers ingested a radiolabeled (99mTc) test meal and scintigraphic images were recorded. Radioactivity in the upper third and whole stomach was calculated to evaluate accommodation. In the barostat procedure, gastric accommodation was evaluated by measuring the maximum volume of the distended balloon. Thereafter, correlation between scintigraphic and barostat accommodation was investigated. Intra‐and inter‐observer variation of the scintigraphic test results were also assessed. Finally, the diagnostic performance of scintigraphy was evaluated by using sumatriptan as a positive control.ResultsMeasurements of accommodation by scintigraphy and barostat correlated (r = 0.524,P< 0.05). Sumatriptan significantly increased scintigraphically measured gastric accommodation (with sumatriptan, 51.5 ± 16.4%; without sumatriptan, 38.4 ± 13.8%) (P< 0.01), and had significantly (P< 0.05) delayed 50% half emptying time at 60, 90, 120, and 150 min after the start of the experiment. The data from repeated scintigraphic tests were highly reproducible (r = 0.804) with significant differences not observed among the investigators (inter‐observer variation = 0.932, intra‐observer variation = 0.898).ConclusionGastric scintigraphy is a useful technique for assessing gastric accommodation and emptying.