Metastatic renal oncocytoma
Metastatic renal oncocytoma
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DOI：
10.1136/jcp.2006.044198
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发表时间：
2007-06-01
影响因子：
3.4
通讯作者：
Gillatt, D. A.
中科院分区：
文献类型：
--
作者：
Oxley, J. D.;Sullivan, J.;Gillatt, D. A.
肾嗜酸细胞瘤在2004年世界卫生组织肾肿瘤分类中被分类为良性肾肿瘤。1转移性肿瘤的病例已被记录，2-4但随后的报告已确定肾肿瘤的亚型具有相似的组织学形态，但具有恶性潜力。这些肿瘤被分类为肾细胞癌（RCC）的嗜酸性变体或嫌色细胞癌。区分这些肿瘤从嗜酸细胞瘤已被证明是困难的，并依赖于组织形态学，免疫组织化学和电子显微镜的组合。仍然有一个假设，如果发生转移，那么肿瘤不应该被归类为肾嗜酸细胞瘤，而应该被称为嗜酸性肾细胞癌。我们报告一位肾脏嗜酸细胞瘤切除后9年出现肝转移的病例。
Renal oncocytomas are classified as benign renal neoplasms in the 2004 World Health Organization classification of renal tumours. 1 Cases of metastatic tumours have been documented, 2–4 but subsequent reports have identified subtypes of renal tumours having similar histological morphology but having malignant potential. These tumours have been classified as either eosinophilic variants of renal cell carcinoma (RCC) or chromophobe carcinomas. Differentiating these tumours from oncocytomas has proved to be difficult and relies on a combination of histological morphology, immunohistochemistry and electron microscopy. There is still a presumption that if metastasis occurs then the tumour should not be classified as a renal oncocytoma and should be called an eosinophilic RCC. We present a patient who presented with liver metastasis 9 years after the removal of a renal oncocytoma.