β-Carotene Is an Important Vitamin A Source for Human

β-Carotene Is an Important Vitamin A Source for Human
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DOI:
10.3945/jn.109.119024
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发表时间:
2010-12-01
影响因子:
4.2
通讯作者:
Biesalski, Hans K.
Biesalski, Hans K.
中科院分区:
医学2区
文献类型:
--
作者:
Grune, Tilman;Lietz, Georg;Biesalski, Hans K.

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类胡萝卜素领域的专家于2009年7月在霍亨海姆共识会议上开会,阐明了β-胡萝卜素的研究现状,并总结了关于β-胡萝卜素的化学特性、生理功能和摄入量的现有知识。专家们讨论了17个问题,并在每个案例中达成了共识答案。这些共识答案基于已发表的有效数据,这些数据经过个别专家的仔细审查,并通过背景陈述进行了证明,确定了β-胡萝卜素对膳食中维生素A总摄入量的影响是复杂的,因为β-胡萝卜素转化为视黄醇的效率不是一个单一的比率,而且是不同的。转换因子已被用于不同国家的各种调查和遵循政府建议,然而,从各种研究中,β-胡萝卜素在实现维生素A推荐摄入量方面的作用是显而易见的。因此,除了阐明β-胡萝卜素的各种功能、分布和摄取外,共识会议特别强调了β-胡萝卜素的维生素A原功能,以及β-胡萝卜素在实现所需/推荐的总维生素A摄入量中的作用。在发达国家和发展中国家,一致认为β-胡萝卜素是维生素A的安全来源,并且β-胡萝卜素的维生素A原功能有助于维生素A的摄入量。
Experts in the field of carotenoids met at the Hohenheim consensus conference in July 2009 to elucidate the current status of beta-carotene research and to summarize the current knowledge with respect to the chemical properties physiological function and intake of beta-carotene The experts discussed 17 questions and reached an agreement formulated in a consensus answer in each case These consensus answers are based on published valid data which were carefully reviewed by the individual experts and are justified here by background statements Ascertaining the impact of beta-carotene on the total dietary intake of vitamin A is complicated because the efficiency of conversion of beta carotene to retinol is not a single ratio and different conversion factors have been used in various surveys and following governmental recommendations within different countries However a role of beta-carotene in fulfilling the recommended intake for vitamin A is apparent from a variety of studies Thus besides elucidating the various functions distribution and uptake of beta-carotene the consensus conference placed special emphasis on the provitamin A function of beta carotene and the role of beta-carotene in the realization of the required/recommended total vitamin A intake in both developed and developing countries There was consensus that beta carotene is a safe source of vitamin A and that the provitamin A function of beta-carotene contributes to vitamin A intake J Nutr 140 2268S-2285S 2010