Effects of Cortical Bone Perforation on Periosteal Distraction: An Experimental Study in the Rabbit Mandible
Effects of Cortical Bone Perforation on Periosteal Distraction: An Experimental Study in the Rabbit Mandible
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DOI：
10.1016/j.joms.2008.06.085
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发表时间：
2009-07-01
影响因子：
1.9
通讯作者：
Ueda, Minoru
中科院分区：
文献类型：
--
作者：
Oda, Tomoo;Kinoshita, Kazuhiko;Ueda, Minoru
目的：为了研究组织反应，采用骨膜牵张与去皮质孔在兔model.Materials和方法：25日本白色兔体重3.2至3.7公斤。去皮质组取颊侧皮质骨，取其骨膜，钻成多孔状。将钛网放置在骨膜和皮质骨之间，有孔或无孔。将牵引螺钉牢固地放置在补片中心下方。在7天的潜伏期后，每天牵开骨膜0.5 mm，连续8天。在4周和8周的巩固期后处死家兔。用密度测定法评价横断面X线片。结果：骨膜牵张后8周，去皮质和不去皮质的新骨形成面积分别为25.7 +/- 5.1 mm（2）和12.9 +/- 3.2 mm（2）（平均值+/- SD）。在这项研究中，骨膜牵引显示更好的骨再生的下颌骨的侧面，而不是没有decoratingholes.Conclusion：骨膜牵引与decoratingholes可以有效地增加萎缩的骨。(C)2009年美国口腔颌面外科医师协会J Oral Maxillofac Surg 67：1478-1485，2009
Purpose: To investigate tissue reactions using periosteal distraction with decorticating holes in a rabbit model.Materials and Methods: Twenty-five Japanese white rabbits weighing 3.2 to 3.7 kg were used. The periosteum was carefully detached, and the buccal cortical bone was porously perforated by drilling in the decortication group. Titanium mesh was placed between the periosteum and the cortical bone, with or without holes. A distraction screw was placed rigidly under the center of the mesh. After a 7-day latency period, the periosteum was distracted 0.5 mm per day for 8 consecutive days. Rabbits were sacrificed after consolidation periods of 4 and 8 weeks. Cross-sectional radiographs were evaluated with densitometry. Specimens were fixed, decalcified, and stained with hematoxylin and eosin.Results: At 8 weeks after periosteal distraction, the area of new bone formation averaged 25.7 +/- 5.1 mm(2) and 12.9 +/- 3.2 mm(2) (mean +/- SD) with and without decortication, respectively. In this study, periosteal distraction showed better bone regeneration on the lateral aspect of mandibles with rather than without decorticating holes.Conclusion: Periosteal distraction with decorticating holes can be effective in augmenting atrophic bone. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67:1478-1485, 2009