Synthesis and physicochemical characterization of fluorescent (E)-2-stilbenyloxyalkylthiouracils and isomer differentiation using EIMS
Synthesis and physicochemical characterization of fluorescent (E)-2-stilbenyloxyalkylthiouracils and isomer differentiation using EIMS
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DOI：
10.1002/jhet.5570410207
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发表时间：
2004-03-01
影响因子：
2.4
通讯作者：
Wendzonka, M
中科院分区：
文献类型：
--
作者：
Wyrzykiewicz, E;Wendzonka, M
合成了12个新的荧光(E)-2-二苯乙烯氧烷基硫氧嘧啶和6-甲基尿嘧啶5a-5l。研究了这些化合物的电致电致光谱碎裂现象。在准确的质量和亚稳转变测量的基础上，提出了碎裂途径。M+强度之间的相关性。并讨论了这些化合物所选择的碎片离子。所获得的数据允许区分异构体。结合异核(HETCOR)谱和化学位移，对这些化合物的H-1和C-13核磁共振谱进行了明确的归属。从这些光谱中得到的数据可以用来区分异构体。
Twelve new fluorescent (E)-2-stilbenyloxyalkylthiouracils and 6-methyluracils 5a-5l were prepared. El induced mass spectral fragmentation of these compounds was investigated. Fragmentation pathways are proposed on the basis of accurate mass and metastable transition measurements. Correlation between the intensities of the M+. and the selected fragment ions of these compounds is discussed. The data obtained permit a distinction of the metamers. The H-1 and C-13 NMR spectra of these compounds were assigned unambiguously using a combination of heteronuclear (HETCOR) spectra and the chemical shifts. The data derived from these spectra can be used to differentiate the isomers.