Domino reaction for the chemo- and stereoselective synthesis of trans-2,3-dihydrobenzofurans from N-thiophosphinyl imines and sulfur ylides.
Domino reaction for the chemo- and stereoselective synthesis of trans-2,3-dihydrobenzofurans from N-thiophosphinyl imines and sulfur ylides.
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DOI：
10.1021/jo2008737
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发表时间：
2011-08
期刊：
影响因子：
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通讯作者：
Peizhong Xie;Liye Wang;Lihua Yang;Erqing Li;Jianze Ma;You Huang;Ruyu Chen
中科院分区：
文献类型：
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作者：
Peizhong Xie;Liye Wang;Lihua Yang;Erqing Li;Jianze Ma;You Huang;Ruyu Chen
研究了水杨基硫代膦酰亚胺与硫叶立德的多米诺成环反应。该方法允许以高产率和优异的化学选择性和立体选择性合成高度取代的反式-2，3-二氢苯并呋喃骨架。
A novel domino annulation between sulfur ylides and salicyl N-thiophosphinyl imines was developed. The method allows the synthesis of a highly substituted trans-2,3-dihydrobenzofuran skeleton with high yield and excellent chemo- and stereoselectivity.