Effects of periodontal treatment on lung function and exacerbation frequency in patients with chronic obstructive pulmonary disease and chronic periodontitis: A 2-year pilot randomized controlled trial

Effects of periodontal treatment on lung function and exacerbation frequency in patients with chronic obstructive pulmonary disease and chronic periodontitis: A 2-year pilot randomized controlled trial
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牙周治疗对慢性阻塞性肺疾病和慢性牙周炎患者肺功能和恶化频率的影响:一项为期 2 年的随机对照试验

DOI:
10.1111/jcpe.12247
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发表时间:
2014-06-01
影响因子:
6.7
通讯作者:
Sun, Zheng
Sun, Zheng
中科院分区:
医学1区
文献类型:
--
作者:
Zhou, Xuan;Han, Jing;Sun, Zheng

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目的评价慢性阻塞性肺疾病(COPD)合并慢性牙周炎(CP)患者牙周治疗的直接疗效。材料与方法在一项先导性随机对照试验中,60例慢性阻塞性肺疾病合并慢性阻塞性肺病患者随机分为3组,分别接受洁治和根面平整(SRP)、牙龈上洁治和口腔卫生指导,而不接受牙周治疗。我们在基线、6个月、1年和2年评估他们的牙周指数、呼吸功能和COPD恶化情况。结果两组患者术后6个月、1年、2年的牙周指标均较对照组有显著改善(P均<0.05)。
Aim To evaluate the direct effects of periodontal therapy in Chronic Obstructive Pulmonary Disease (COPD) patients with chronic periodontitis (CP). Materials and Methods In a pilot randomized controlled trial, 60 COPD patients with CP were randomly assigned to receive scaling and root planing (SRP) treatment, supragingival scaling treatment, or oral hygiene instructions only with no periodontal treatment. We evaluated their periodontal indexes, respiratory function, and COPD exacerbations at baseline, 6months, 1, and 2years. Results Compared with the control group, measurements of periodontal indexes were significantly improved in patients in two treatment groups at 6-month, 1-year, and 2-year follow-up (all p