Cellular and molecular aspects of iron and immune function
Cellular and molecular aspects of iron and immune function
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DOI：
10.1017/s002966510000077x
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发表时间：
2000-11-01
影响因子：
7
通讯作者：
Mulero, V
中科院分区：
文献类型：
--
作者：
Brock, JH;Mulero, V
铁在免疫系统和防御感染中起着至关重要的作用。然而，铁在分子和细胞水平上影响这些过程的方式的许多方面尚不清楚。本综述总结了 Fe 在淋巴细胞活化和增殖中的作用，并讨论了巨噬细胞如何处理 Fe。
Fe plays a critical role in the immune system and defence against infection. However, many aspects of the way in which Fe influences these processes at the molecular and cellular level are unclear. The present review summarizes the role of Fe in lymphocyte activation and proliferation, and discusses how Fe is handled by macrophages.