In vitro antiplaque effects of antiseptic phenols.
In vitro antiplaque effects of antiseptic phenols.
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防腐酚的体外抗牙菌斑作用。
DOI：
10.1902/jop.1977.48.3.156
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发表时间：
1977
影响因子：
4.3
通讯作者：
R. Genco
中科院分区：
文献类型：
--
作者：
R. Evans;P. Baker;R. A. Coburn;S. Fischman;R. Genco
我们在体外测试了几种已知具有防腐剂作用的酚类物质，它们能够吸附在唾液涂层的牙釉质上，并随后抑制牙菌斑的形成。研究发现，3,5,4'-三溴水杨酸苯胺可有效抑制粘螺旋体、纳氏螺旋体、变形螺旋体和血螺旋体的生长和斑块形成。双溴水杨酸对粘虫有效。其他酚类（己基间苯二酚、百里香酚、苯基酚和酚磺酸锌）对体外生长或斑块形成没有抑制作用。
Several phenols known to be antiseptics were tested in vitro for their ability to adsorb to saliva-coated enamel and subsequently inhibit plaque formation. 3,5,4'-tribromosalicylanilide was found to be effective against growth and plaque formation of A viscosus, A naeslundii, S mutans and S sanguis. Dibromsalicil was effective against A viscosus. The other phenols (hexylresorcinol, thymol, phenylphenol and zinc phenolsulfonate) did not inhibit in vitro growth or plaque formation.