Standardization of the Caffeine Halothane Muscle Contracture Test
Standardization of the Caffeine Halothane Muscle Contracture Test
复制标题
咖啡因氟烷肌肉挛缩测试的标准化
DOI：
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发表时间：
1989
影响因子：
5.7
通讯作者：
M. G. Larach
中科院分区：
文献类型：
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作者：
M. G. Larach
1987年11月4日至6日，来自北美24个恶性高热（MH）检测中心的47名代表在伊利诺斯州的Lake海崖开会，讨论使用咖啡因和氟烷进行骨骼肌挛缩检测的标准化方案的制定。咖啡因氟烷挛缩试验是一种需要使用新鲜肌肉的筛查试验，用于诊断MH易感性。欧洲恶性高热小组先前已在欧洲建立了咖啡因氟烷挛缩试验的标准化方案（见第515页）。欧洲方案与北美方案在几个次要方面存在差异，主要差异涉及肌肉暴露于2%而不是3%氟烷。本文代表了在美国恶性高热协会和恶性高热协会的赞助下召开的47名代表达成的共识，这些代表将在下文中被称为北美MH组。北方的建议议定书
On November 4 6 , 1987, 47 representatives from 24 North American malignant hyperthermia (MH) testing centers met in Lake Bluff, Illinois, to discuss development of a standardized protocol for skeletal muscle contracture testing using caffeine and halothane. The caffeine halothane contracture test is a screening test that requires use of fresh muscle and is used in the diagnosis of MH susceptibility. A standardized protocol for caffeine halothane contracture testing has been previously established in Europe by the European Malignant Hyperpyrexia Group (see p. 515). The European protocol differs in several minor aspects from the North American protocol, with the primary difference involving exposure of muscle to 2% rather than 3% halothane. This article represents the consensus achieved by the 47 representatives who shall hereafter be referred to as the North American MH Group who convened under the sponsorship of the Malignant Hyperthermia Association of the United States and the Malignant Hyperthermia Association. The recommended protocol of the North