Neural activity related to reaching and grasping in rostral and caudal regions of rat motor cortex
Neural activity related to reaching and grasping in rostral and caudal regions of rat motor cortex
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DOI：
10.1016/s0166-4328(97)00157-5
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发表时间：
1998-08-01
影响因子：
2.7
通讯作者：
Hyland, B
中科院分区：
文献类型：
--
作者：
Hyland, B
本研究的目的是评估大鼠运动皮质神经活动与自定进度的抓握动作的关系。总体而言，神经元活动中大约 40% 的兴奋性调节和 60% 的抑制性调节在到达发作之前就开始了。这些数据与大鼠运动皮层在伸手运动的启动和控制中的作用一致。此外，虽然到达的时间很短，但30%的兴奋和抑制是在到达过程中开始的。在触及过程中发生的这种调节的存在与先前显示皮质神经元在触及后期的活动的数据一致，并且表明皮质神经元大量参与控制最近描述的与大鼠中观察到的抓握相关的复杂运动。这些特征在大鼠运动皮层尾部和吻部细分的神经元中大致相似。 (C) 1998 Elsevier Science B.V. 保留所有权利。
The objective of this study was to assess the relation of motor cortical neural activity in the rat to self-paced reach-to-grasp movements. Overall, around 40% of excitatory and 60% of inhibitory modulations in neuronal activity began prior to reach onset. These data are consistent with a role for rat motor cortex in the initiation and control of the reaching movement. In addition, although the reach only lasted a short time, 30% of excitations and inhibitions began while it was in progress. The existence of such modulations occurring during the reach is consistent with previous data showing activity of cortical neurons late in the reach, and suggests a heavy involvement of cortical neurons in controlling the recently described, complex movements associated with grasping that are seen in the rat. These features were broadly similar in neurones from both the caudal and rostral subdivisions of rat motor cortex. (C) 1998 Elsevier Science B.V. All rights reserved.