Decreased Computerized Tomography Numbers in Patients With Presenile Dementia: Detection in Patients With Otherwise Normal Scans
Decreased Computerized Tomography Numbers in Patients With Presenile Dementia: Detection in Patients With Otherwise Normal Scans
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老年前期痴呆患者的计算机断层扫描数量减少：在其他扫描正常的患者中进行检测
DOI：
10.1001/archneur.1980.00500560031002
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发表时间：
1980
期刊：
影响因子：
29
通讯作者：
H. Levine
中科院分区：
文献类型：
--
作者：
M. Naeser;C. Gebhardt;H. Levine
·50多岁的患者表现出痴呆症（可能是阿尔茨海默病）的临床症状，通常计算机断层扫描（CT）显示正常。本研究检查了半卵圆中心切片中白色物质中169像素样本的平均CT值。切片大小范围从6，800到9，000像素;所有都没有对比度增强。6例非痴呆病例（CT值41及以上）的CT值高于14例痴呆病例（CT值40及以下）。观察到两组之间的平均CT数不重叠，与是否存在突出的脑沟无关。7例老年性痴呆患者的CT值也同样较低。痴呆症和抑郁症之间的鉴别诊断可能更好地帮助研究CT数字，而不是突出的脑沟的存在。
• Patients in their 50s who show clinical signs of dementia (possible Alzheimer's disease) often have computerized tomographic (CT) scans that appear normal. This study examined the mean CT number within a 169-pixel sample in white matter in the centrum semiovale slice. Slice sizes ranged from 6,800 to 9,000 pixels; all were without contrast enhancement. The CT numbers were higher for six nondementia cases (CT numbers of 41 and above) than for 14 dementia cases (CT numbers of 40 and below). The non-overlap in mean CT numbers between the two groups was observed independent of the presence or absence of prominent sulci. Similar low CT numbers were observed for seven patients with senile dementia. Differential diagnosis between dementia and depression may be better aided by studying the CT numbers rather than the presence of prominent sulci.