Changes in mortality due to major alcohol-related diseases in four Nordic countries, France and Germany between 1980 and 2009: a comparative age-period-cohort analysis
Changes in mortality due to major alcohol-related diseases in four Nordic countries, France and Germany between 1980 and 2009: a comparative age-period-cohort analysis
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DOI：
10.1111/add.12989
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发表时间：
2015-09-01
期刊：
影响因子：
6
通讯作者：
Torronen, Jukka
中科院分区：
文献类型：
--
作者：
Kraus, Ludwig;Osthus, Stale;Torronen, Jukka
目的探讨不同饮酒习惯和饮酒政策国家中年龄、时期和队列对酒精相关死亡率时间趋势的影响。2000年，法国和德国发生了与酒精有关的死亡病例，1980年至2009年之间的84岁。测量死亡率数据来自国家死亡原因登记处，涵盖ICD编码酒精性精神病，酒精使用障碍，酒精性肝病和酒精毒性作用。发现两种性别的周期和队列均具有显著性[效应值和置信区间（CI）见支持性信息，表S1]。在丹麦、芬兰和德国，酒精相关死亡率随时间的变化呈上升趋势，而在瑞典，酒精相关死亡率呈略微下降趋势;在挪威，酒精相关死亡率呈倒U形曲线，在法国，酒精相关死亡率呈U形曲线;与1960年以前出生的队列相比，1960年代及以后出生的队列中，酒精相关死亡率的风险大幅下降。国家间的成对比较显示，
AimsTo investigate age, period and cohort effects on time trends of alcohol-related mortality in countries with different drinking habits and alcohol policies.Design and settingAge-period-cohort (APC) analyses on alcohol-related mortality were conducted in Denmark, Finland, Norway, Sweden, France and Germany.ParticipantsCases included alcohol-related deaths in the age range 20-84 years between 1980 and 2009.MeasurementsMortality data were taken from national causes of death registries and covered the ICD codes alcoholic psychosis, alcohol use disorders, alcoholic liver disease and toxic effect of alcohol.FindingsIn all countries changes across age, period and cohort were found to be significant for both genders [effect value with confidence interval (CI) shown in Supporting information, Table S1]. Period effects pointed to an increase in alcohol-related mortality in Denmark, Finland and Germany and a slightly decreasing trend in Sweden, while in Norway an inverse U-shaped curve and in France a U-shaped curve was found. Compared with the cohorts born before 1960, the risk of alcohol-related mortality declined substantially in cohorts born in the 1960s and later. Pairwise between-country comparisons revealed more statistically significant differences for period (P