Significance of rescue hybrid endoscopic submucosal dissection in difficult colorectal cases.

Significance of rescue hybrid endoscopic submucosal dissection in difficult colorectal cases.
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DOI:
10.5946/ce.2022.268
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发表时间:
2023-11
期刊:
影响因子:
2.5
通讯作者:
Itoi T
Itoi T
中科院分区:
其他
文献类型:
--
作者:
Yamaguchi H;Fukuzawa M;Kawai T;Muramatsu T;Matsumoto T;Uchida K;Koyama Y;Madarame A;Morise T;Kono S;Naito S;Nagata N;Sugimoto M;Itoi T

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混合式内镜粘膜下剥离术(ESD)是在病变周围切开,并在粘膜下剥离后进行圈套,在结直肠手术中具有一些优点,包括缩短手术时间和防止穿孔。然而,其在困难结直肠 ESD 病例中挽救性切除的价值仍不清楚。本研究评估了救援混合 ESD (RH-ESD) 的实用性。 我们将 364 例结直肠 ESD 手术分为传统 ESD 组(C-ESD,n=260)、预定混合 ESD 组(SH-ESD,n=69)和 RH-ESD 组(n=35),并比较其临床结果。 切除时间按以下顺序显着缩短:RH-ESD(149 [90–197] 分钟)>C-ESD(90 [60–140] 分钟)>SH-ESD(52 [29–80] 分钟)。整块切除率按以下顺序显着增加:RH-ESD (48.6%)、SH-ESD (78.3%) 和 C-ESD (97.7%)。对 RH-ESD 分片切除相关因素的分析显示,分片切除组的粘膜下剥离率 (25% [20%–30%]) 显着低于整块切除组 (40% [20%–60%])。 由于整块切除率低,RH-ESD 在治愈性切除方面无效,但对于避免手术很有用。
Hybrid endoscopic submucosal dissection (ESD), in which an incision is made around a lesion and snaring is performed after submucosal dissection, has some advantages in colorectal surgery, including shorter procedure time and preventing perforation. However, its value for rescue resection in difficult colorectal ESD cases remains unclear. This study evaluated the utility of rescue hybrid ESD (RH-ESD). We divided 364 colorectal ESD procedures into the conventional ESD group (C-ESD, n=260), scheduled hybrid ESD group (SH-ESD, n=69), and RH-ESD group (n=35) and compared their clinical outcomes. Resection time was significantly shorter in the following order: RH-ESD (149 [90–197] minutes) >C-ESD (90 [60–140] minutes) >SH-ESD (52 [29–80] minutes). The en bloc resection rate increased significantly in the following order: RH-ESD (48.6%), SH-ESD (78.3%), and C-ESD (97.7%). An analysis of factors related to piecemeal resection of RH-ESD revealed that the submucosal dissection rate was significantly lower in the piecemeal resection group (25% [20%–30%]) than in the en bloc resection group (40% [20%–60%]). RH-ESD was ineffective in terms of curative resection because of the low en bloc resection rate, but was useful for avoiding surgery.
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