Hand-Held Transistor Based Electrical and Multiplexed Chemical Sensing System
Hand-Held Transistor Based Electrical and Multiplexed Chemical Sensing System
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DOI：
10.1021/acssensors.6b00520
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发表时间：
2016-12-01
期刊：
影响因子：
8.9
通讯作者：
Levon, Kalle
中科院分区：
文献类型：
--
作者：
Kaisti, Matti;Boeva, Zhanna;Levon, Kalle
我们描述了一种手持式传感系统，使用基于晶体管的多路复用平台和将电化学信息无线耦合到智能手机的检测器。定制一次性平台采用离子敏感 FET (ISFET) 技术。通过简单的表面修饰，该设计可以以低成本测试多种分析物。我们使用 K+ 作为物种分析物示例，将我们的读出装置与商用电位计进行了比较。所开发的传感系统具有稍微更好的检测限，并且明显不易受到外部噪声的影响，而外部噪声通常是通过电位计观察到的。设计的平台采用金表面标准电子工艺制造，并使用商用分立晶体管作为换能元件。可大批量生产，产量高，成本低。为了避免改良固态电极通常发生的漂移，我们在电导体（金垫）和离子导电离子选择性膜之间加入了一个转换层。首次使用掺杂二壬基萘磺酸的聚苯胺(PANI-DNNSA)作为换能层。与没有换能层的配置相比，PANT-DNNSA 层显着减少了电极的漂移。该系统易于使用基于晶体管的检测，可以针对各种现有的电位测试进行修改。
We describe a hand-held sensing system using a transistor based multiplexed platform and a detector that couples the electrochemical information wirelessly to a smartphone. The custom disposable platform exploits the ion-sensitive FET (ISFET) technology. Via simple surface modifications the design allows a broad range of analytes to be tested with low cost. We compared our read-out device to a commercial potentiometer using K+ as an example species analyte. The developed sensing system has a slightly better limit of detection and is notably less susceptible to external noise which is commonly observed with potentiometers. The designed platform is fabricated using standard electronic processes with gold surface and we used commercial discrete transistors as the transducing element. It can be mass produced with high yield and low cost. To circumvent the drift that typically occurs with modified solid state electrodes we incorporated a transducing layer between the electric conductor (gold pad) and the ionically conducting ion-selective membrane. The polyaniline doped with dinonylnaphtalene sulfonic acid (PANI-DNNSA) was used as a transducing layer for the first time. The PANT-DNNSA layer significantly reduces the drift of the electrodes compared to a configuration without the transducing layer. The system is easy to use with a transistor based detection that can be modified for a vast variety of existing potentiometric tests.