Neuroimaging studies of working memory: A meta-analysis
Neuroimaging studies of working memory: A meta-analysis
复制标题
DOI：
10.3758/cabn.3.4.255
复制
发表时间：
2003-12-01
影响因子：
2.9
通讯作者：
Smith, Edward E.
中科院分区：
文献类型：
--
作者：
Wager, Tor D.;Smith, Edward E.
我们对60项关于工作记忆的神经成像(PET和fMRI)研究进行了Meta分析，考虑了三种类型的存储材料(空间、语言和对象)，三种执行功能(持续更新工作记忆、对时间顺序的记忆和对工作记忆中信息的处理)，以及材料和执行功能之间的相互作用。对材料类型的分析表明，在后部皮质的空间和非空间存储之间存在预期的背腹分离，但在额叶皮质没有。口头工作记忆中的左额优势得到了一定的支持，但仅限于执行要求较低的任务。对于空间工作记忆，执行需求增加了额叶皮质的右侧化。需要执行加工的任务通常比只进行存储的任务产生更多的背侧额叶激活，但并不是所有的执行加工都表现出这种模式。当WM必须持续更新和对时间顺序的记忆必须保持时，位于额叶上皮质的Brodmann‘s Areas(BAS)6、8和9反应最大。位于前额叶腹侧皮质的右脑10号和47号对操纵的要求(包括双重任务要求或心理操作)的反应更为频繁。BA7位于顶叶后皮质，参与所有类型的执行功能。最后，我们考虑了潜在的第四种执行功能：对要存储在WM中的刺激特征的选择性注意，这导致在存储任务中激活内侧前额叶皮质(BA 32)的可能性增加。
We performed meta-analyses on 60 neuroimaging (PET and fMRI) studies of working memory (WM), considering three types of storage material (spatial, verbal, and object), three types of executive function (continuous updating of WM, memory for temporal order, and manipulation of information in WM), and interactions between material and executive function. Analyses of material type showed the expected dorsal-ventral dissociation between spatial and nonspatial storage in the posterior cortex, but not in the frontal cortex. Some support was found for left frontal dominance in verbal WM, but only for tasks with low executive demand. Executive demand increased right lateralization in the frontal cortex for spatial WM. Tasks requiring executive processing generally produce more dorsal frontal activations than do storage-only tasks, but not all executive processes show this pattern. Brodmann's areas (BAs) 6, 8, and 9, in the superior frontal cortex, respond most when WM must be continuously updated and when memory for temporal order must be maintained. Right BAs 10 and 47, in the ventral frontal cortex, respond more frequently with demand for manipulation (including dual-task requirements or mental operations). BA 7, in the posterior parietal cortex, is involved in all types of executive function. Finally, we consider a potential fourth executive function: selective attention to features of a stimulus to be stored in WM, which leads to increased probability of activating the medial prefrontal cortex(BA 32) in storage tasks.