Comparison of the prognostic value of myocardial perfusion imaging using a CZT-SPECT camera with a conventional anger camera
Comparison of the prognostic value of myocardial perfusion imaging using a CZT-SPECT camera with a conventional anger camera
复制标题
DOI：
10.1007/s12350-016-0618-9
复制
发表时间：
2017-02-01
影响因子：
2.4
通讯作者：
Camargo, Gabriel
中科院分区：
文献类型：
--
作者：
Lima, Ronaldo;Peclat, Thais;Camargo, Gabriel
背景。近年来的研究表明，使用碲化镉锌（CZT）相机进行心肌灌注成像（MPI）检查速度快，辐射剂量小，但其预后信息与专用心脏Na-I SPECT相机的预后信息比较的数据很少。本研究的目的是比较在CZT-SPECT中使用低剂量超快方案和传统方法对MPI的预后价值。第1组在常规相机中进行为期2天的MIBI治疗，第2组在CZT相机中进行为期1天的MIBI治疗。将MPI分为正常和异常，计算灌注评分。采用倾向评分匹配方法。3554例患者随访33+/-8个月。1组和2组患者的年龄、性别、体重指数、危险因素、既往血运重建术和药物应激使用情况分布相似。1组异常扫描较多，评分高于2组。正常扫描组1的年化硬事件发生率较高，但血运重建频率与正常组2相似。两组扫描异常患者的事件发生率相似。在CZT-SPECT中MPI的新方案显示与专用心脏Na-I SPECT相机获得的预后结果相似，正常扫描患者的硬事件发生率较低。
Background. Recent studies have shown that myocardial perfusion imaging (MPI) in cadmium- zinc-telluride (CZT) cameras allow faster exams with less radiation dose but there are little data comparing its prognosis information with that of dedicated cardiac Na-I SPECT cameras Objective. The objective of this study is to compare the prognostic value of MPI using an ultrafast protocol with low radiation dose in a CZT-SPECT and a traditional one.Methods. Group 1 was submitted to a two-day MIBI protocol in a conventional camera, and group 2 was submitted to a 1-day MIBI protocol in CZT camera. MPI were classified as normal or abnormal, and perfusion scores were calculated. Propensity score matching methods were performedResults. 3554 patients were followed during 33+/-8 months. Groups 1 and 2 had similar distribution of age, gender, body mass index, risk factors, previous revascularization, and use of pharmacological stress. Group 1 had more abnormal scans, higher scores than group 2. Annualized hard events rate was higher in group 1 with normal scans but frequency of revascularization was similar to normal group 2. Patients with abnormal scans had similar event rates in both groupsConclusion. New protocol of MPI in CZT-SPECT showed similar prognostic results to those obtained in dedicated cardiac Na-I SPECT camera, with lower prevalence of hard events in patients with normal scan.