Is an Acoustic Neuroma an Epiarachnoid or Subarachnoid Tumor?
Is an Acoustic Neuroma an Epiarachnoid or Subarachnoid Tumor?
复制标题
DOI：
10.1227/neu.0b013e318208f37f
复制
发表时间：
2011-04-01
期刊：
影响因子：
4.8
通讯作者：
Yokoyama, Munehiro
中科院分区：
文献类型：
--
作者：
Kohno, Michihiro;Sato, Hiroaki;Yokoyama, Munehiro
背景：关于听神经瘤是蛛网膜外肿瘤还是蛛网膜下肿瘤存在争议。目的：通过回顾性检查118例连续手术的听神经瘤患者来澄清这一点。方法：蛛网膜外肿瘤是指将蛛网膜皱襞（双层蛛网膜）向脑干移动后，肿瘤表面无蛛网膜。相反，蛛网膜下腔肿瘤的特征是蛛网膜皱襞移动后，蛛网膜仍保留在肿瘤表面。基于这一假设，我们利用术中视图以及光镜和电镜证实蛛网膜襞移动后蛛网膜的存在。结果：118例患者中，86例（73%）明确判断肿瘤为蛛网膜下肿瘤，2例（2%）为蛛网膜外肿瘤，而其余30例患者（25%）难以明确判断。结论：大多数声学肿瘤神经瘤是蛛网膜下腔肿瘤，而蛛网膜外肿瘤则相当不常见。
BACKGROUND: There are arguments about whether acoustic neuromas are epiarachnoid or subarachnoid tumors.OBJECTIVE: To retrospectively examine 118 consecutively operated-on patients with acoustic neuromas to clarify this point.METHODS: Epiarachnoid tumors are defined by the absence of an arachnoid membrane on the tumor surface after moving the arachnoid fold (double layers of the arachnoid membrane) toward the brainstem. In contrast, subarachnoid tumors are characterized by the arachnoid membrane remaining on the tumor surface after moving the arachnoid fold. Based on this hypothesis, we used intraoperative views and light and electron microscopy to confirm the existence of an arachnoid membrane after the arachnoid fold had been moved.RESULTS: The tumors were clearly judged to be subarachnoid tumors in 86 of 118 patients (73%), an epiarachnoid tumor in 2 patients (2%), whereas a clear judgment was difficult to make in the remaining 30 patients (25%).CONCLUSION: The majority of acoustic neuromas are subarachnoid tumors, with epiarachnoid tumors being considerably less common.