New features of the blocks database servers
New features of the blocks database servers
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DOI：
10.1093/nar/27.1.226
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发表时间：
1999-01-01
影响因子：
14.9
通讯作者：
Pietrokovski, S
中科院分区：
文献类型：
--
作者：
Henikoff, JG;Henikoff, S;Pietrokovski, S
Blocks是代表保守蛋白质区域的无空位多序列比对，Blocks数据库由来自记录的蛋白质家族的块组成。万维网（http：//www.blocks. fhcrc.org）和电子邮件（blocks@blocks.fhcrc.org）服务器提供用于同源性搜索和用于分析蛋白质家族关系的工具。新的增强功能包括一个多重比对处理器，该处理器将这些工具的使用扩展到数据库中不存在的家族的多重比对，以及一个PCR引物设计器，该设计器实现了一种新的基因分离策略。
Blocks are ungapped multiple sequence alignments representing conserved protein regions, and the Blocks Database consists of blocks from documented protein families. World Wide Web (http://www.blocks. fhcrc.org) and Email (blocks@blocks.fhcrc.org) servers provide tools for homology searching and for analyzing protein family relationships. New enhancements include a multiple alignment processor that extends the use of these tools to imported multiple alignments of families not present in the database and a PCR primer designer that implements a new strategy for gene isolation.