Evaluating novel approaches for estimating awake and sleep blood pressure: design of the Better BP Study - a randomised, crossover trial.
Evaluating novel approaches for estimating awake and sleep blood pressure: design of the Better BP Study - a randomised, crossover trial.
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评估评估清醒和睡眠血压的新方法：更好的BP研究设计-一项随机交叉试验。
DOI：
10.1136/bmjopen-2021-058140
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发表时间：
2022-06-06
期刊：
影响因子：
2.9
通讯作者：
Shimbo, Daichi
中科院分区：
文献类型：
--
作者：
Cepeda, Maria;Hubbard, Demetria;Oparil, Suzanne;Schwartz, Joseph E.;Jaeger, Byron C.;Hardy, Shakia T.;Medina, Julia;Chen, Ligong;Muntner, Paul;Shimbo, Daichi
对于许多人来说，血压（BP）水平在医疗办公室与办公室外测量时有所不同。与在办公室测量的血压相比，办公室外血压与心血管疾病（CVD）事件的相关性更强。许多BP指南建议在办公室外测量BP，以确认在办公室获得的水平。动态血压监测（ABPM）可以评估办公室外的血压，但在许多美国实践中不可用，有些人觉得不舒服。更好的BP研究的目的是（1）测试与参加的办公室BP相比，无人值守的办公室BP是否更接近于ABPM上的清醒BP，（2）评估通过家庭BP监测（HBPM）评估的睡眠BP是否与整晚ABPM的睡眠BP一致，以及（3）比较无人值守与参加的办公室BP的关联强度，无监护的办公室血压与清醒时ABPM的血压，以及HBPM的睡眠血压与有终末器官损伤标志物的ABPM的血压。我们在亚拉巴马的伯明翰和纽约的纽约招募了630名未服用抗高血压药物的成年人。参与者在一周内的两次访视中的每一次访视期间，使用自动血压计测量办公室BP设备，以随机顺序在有（参加）和无（无人参加）技术人员在场的情况下测量办公室BP。在这些访问之后，参与者以随机顺序完成24小时的ABPM和一晚的HBPM。心理社会因素、人体测量学、左心室质量指数和白蛋白与肌酐比值也正在评估中。这项研究得到了亚拉巴马大学伯明翰分校和哥伦比亚大学医学中心机构审查委员会的批准。研究结果将在科学会议上传播，并发表在同行评审的期刊上。 NCT 04307004。
For many people, blood pressure (BP) levels differ when measured in a medical office versus outside of the office setting. Out-of-office BP has a stronger association with cardiovascular disease (CVD) events compared with BP measured in the office. Many BP guidelines recommend measuring BP outside of the office to confirm the levels obtained in the office. Ambulatory BP monitoring (ABPM) can assess out-of-office BP but is not available in many US practices and some individuals find it uncomfortable. The aims of the Better BP Study are to (1) test if unattended office BP is closer to awake BP on ABPM compared with attended office BP, (2) assess if sleep BP assessed by home BP monitoring (HBPM) agrees with sleep BP from a full night of ABPM and (3) compare the strengths of associations of unattended versus attended office BP, unattended office BP versus awake BP on ABPM and sleep BP on HBPM versus ABPM with markers of end-organ damage. We are recruiting 630 adults not taking antihypertensive medication in Birmingham, Alabama, and New York, New York. Participants are having their office BP measured with (attended) and without (unattended) a technician present, in random order, using an automated oscillometric office BP device during each of two visits within one week. Following these visits, participants complete 24 hours of ABPM and one night of HBPM, in random order. Psychosocial factors, anthropometrics, left ventricular mass index and albumin-to-creatinine ratio are also being assessed. This study was approved by the University of Alabama at Birmingham and the Columbia University Medical Center Institutional Review Boards. The study results will be disseminated at scientific conferences and published in peer-reviewed journals. NCT04307004.
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影响因子：
2.7
作者：
通讯作者：
--
影响因子：
24
作者：
Schwartz JE;Muntner P;Kronish IM;Burg MM;Pickering TG;Bigger JT;Shimbo D
通讯作者：
Shimbo D
影响因子：
39.2
作者：
Shimbo D;Abdalla M;Falzon L;Townsend RR;Muntner P
通讯作者：
Muntner P
影响因子：
4.9
作者：
Myers, Martin G.;Valdivieso, Miguel;Kiss, Alexander
通讯作者：
Kiss, Alexander
DOI：
10.1161/hypertensionaha.116.07553
发表时间：
2016-08
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Booth JN 3rd;Diaz KM;Seals SR;Sims M;Ravenell J;Muntner P;Shimbo D
通讯作者：
Shimbo D