A Comparison of the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study and American Migraine Prevalence and Prevention (AMPP) Study: Demographics and Headache-Related Disability.
A Comparison of the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study and American Migraine Prevalence and Prevention (AMPP) Study: Demographics and Headache-Related Disability.
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作者：
Lipton RB;Manack Adams A;Buse DC;Fanning KM;Reed ML
比较美国偏头痛患病率和预防（AMPP）和慢性偏头痛流行病学和结局（CaMEO）研究的方法和基线特征。AMPP和CaMEO研究是最大的纵向努力，旨在提高我们对美国发作性和慢性偏头痛的理解。这些研究有互补的长处和短处。该分析比较和对比了AMPP和CaMEO研究的研究方法和参与率。然后，我们比较和对比基线结果的人口统计学特征，头痛的特点，和残疾的偏头痛残疾评估量表（MIDAS）的人与发作性和慢性偏头痛。AMPP和CaMEO样本来自代表美国人群的样本组。AMPP研究使用邮寄问卷收集数据，而CaMEO依赖于网络调查方法。AMPP的应答率（64.8%）高于CaMEO（16.5%）。两项研究均使用美国偏头痛研究/AMPP诊断模块评估头痛特征。根据头痛疾病的国际分类，这两个人都确定了发作性（<15头痛天/月）和慢性偏头痛（≥15头痛天/月）。AMPP在5年内每年收集数据，而CaMEO在15个月内每季度收集数据。基线人口统计学分布基本相似，表明每项研究广泛代表美国人群。患有慢性偏头痛的偏头痛患者的比例相似（AMPP，6.6%; CaMEO，8.8%）。对于慢性偏头痛（AMPP：男性= 21.7，女性= 20.0; CaMEO：男性= 20.0，女性= 20.0）和发作性偏头痛（AMPP：男性= 1.7，女性= 2.0; CaMEO：男性= 2.0，女性= 3.0），受访者的中位头痛频率（天/月）相似。在两项研究中，慢性偏头痛的中位MIDAS评分（重度残疾[IV级]; AMPP：男性= 33.0，女性= 45.0; CaMEO：男性= 32.0，女性= 38.0）显著高于发作性偏头痛（轻度/轻度残疾[I/II级]; AMPP：男性= 3.0，女性= 6.0; CaMEO：男性= 4.0，女性= 7.0）。在两项慢性偏头痛研究中，中度/重度残疾（III/IV级）的发生率（AMPP：男性= 66.9%，女性= 78.9%; CaMEO：男性= 71.0%，女性= 82.6%）显著高于发作性偏头痛（AMPP：男性= 23.0%，女性= 31.8%; CaMEO：男性= 26.7%，女性= 37.9%）。在这两项研究中，经历中度/重度残疾的女性受访者多于男性受访者。AMPP和CaMEO是纵向队列研究，使用不同的方法，但在人口统计学特征、头痛频率和头痛相关残疾方面产生了相似的结果。这两项研究都发现，慢性偏头痛患者与发作性偏头痛患者相比，头痛相关残疾更严重。
To compare the methods and baseline characteristics of the American Migraine Prevalence and Prevention (AMPP) and Chronic Migraine Epidemiology and Outcomes (CaMEO) studies. The AMPP and CaMEO studies are the largest longitudinal efforts designed to improve our understanding of episodic and chronic migraine in the United States. The studies have complementary strengths and weaknesses. This analysis compares and contrasts the study methods and participation rates of the AMPP and CaMEO studies. We then compare and contrast baseline results in terms of demographic characteristics, headache features, and disability as measured by the Migraine Disability Assessment Scale (MIDAS) among people with episodic and chronic migraine. AMPP and CaMEO sampled from panels constructed to be representative of the US population. The AMPP Study collected data using a mailed questionnaire while CaMEO relied on a web survey methodology. Response rates were higher in AMPP (64.8%) than in CaMEO (16.5%). Both studies assessed headache features using the American Migraine Study/AMPP diagnostic module. Both identified persons with episodic (<15 headache days/month) and chronic migraine (≥15 headache days/month) based on the International Classification of Headache Disorders. AMPP collected data annually over 5 years, while CaMEO collected data quarterly over 15 months. Baseline demographic distribution was generally similar, indicating that each study was broadly representative of the US population. The proportion of persons with migraine who had chronic migraine was similar (AMPP, 6.6%; CaMEO, 8.8%). Respondents had similar median headache frequency (days/month) by sex for chronic migraine (AMPP: men = 21.7, women = 20.0; CaMEO: men = 20.0, women = 20.0) and episodic migraine (AMPP: men = 1.7, women = 2.0; CaMEO: men = 2.0, women = 3.0). Median MIDAS scores were substantially higher in both studies for chronic migraine (severe disability [Grade IV]; AMPP: men = 33.0, women = 45.0; CaMEO: men = 32.0, women = 38.0) than episodic migraine (little/mild disability [Grade I/II]; AMPP: men = 3.0, women = 6.0; CaMEO: men = 4.0, women = 7.0). Rates of moderate/severe disability (Grade III/IV) were substantially higher in both studies for chronic migraine (AMPP: men = 66.9%, women = 78.9%; CaMEO: men = 71.0%, women = 82.6%) than episodic migraine (AMPP: men = 23.0%, women = 31.8%; CaMEO: men = 26.7%, women = 37.9%). More women than men respondents in both studies experienced moderate/severe disability. AMPP and CaMEO are longitudinal cohort studies that used different methods, but yielded similar results for demographic features, headache frequency, and headache‐related disability. Both studies found more severe headache‐related disability in those with chronic versus episodic migraine.
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影响因子：
4.9
作者：
Bigal, ME;Kolodner, KB;Lipton, RB
通讯作者：
Lipton, RB
影响因子：
9.9
作者：
Lipton, R. B.;Bigal, M. E.;Stewart, W. F.
通讯作者：
Stewart, W. F.
影响因子：
11
作者：
Buse, D. C.;Manack, A.;Lipton, R. B.
通讯作者：
Lipton, R. B.
影响因子：
5
作者：
Dodick DW;Loder EW;Manack Adams A;Buse DC;Fanning KM;Reed ML;Lipton RB
通讯作者：
Lipton RB
影响因子：
5
作者：
Lipton, Richard B.;Serrano, Daniel;Buse, Dawn C.
通讯作者：
Buse, Dawn C.