BEHAVIOR AND CORTICOSTEROID RESPONSE OF MAUDSLEY REACTIVE AND NONREACTIVE RATS IN THE OPEN-FIELD AND FORCED SWIMMING TEST

BEHAVIOR AND CORTICOSTEROID RESPONSE OF MAUDSLEY REACTIVE AND NONREACTIVE RATS IN THE OPEN-FIELD AND FORCED SWIMMING TEST
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DOI:
10.1016/0031-9384(91)90513-n
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发表时间:
1991-07-01
影响因子:
2.9
通讯作者:
ABEL, EL
ABEL, EL
中科院分区:
医学3区
文献类型:
--
作者:
ABEL, EL

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Maudsley反应性(MR)和非反应性(MNRA)雄性大鼠进行了测试,在开放领域和强迫游泳试验。 MR大鼠排便更多,比MNRA大鼠在旷场活动少。 MR大鼠也排便更多,但在强迫游泳试验中更不动。 这两种菌株在基础皮质类固醇水平或皮质类固醇水平对任一测试的反应方面没有显著差异。 这些结果表明,在各种测试中MR大鼠表现出的排便率增加并不表明“情绪性”或压力水平的普遍增加。
Maudsley reactive (MR) and nonreactive (MNRA) male rats were tested in the open field and in the forced swimming test. MR rats defecated more and were less active than MNRA rats in the open field. MR rats also defecated more, but were more immobile in the forced swim test. The two strains did not differ significantly in basal corticosteroid levels or corticosteroid levels in response to either test. These results suggest that the increased defecation rates exhibited by MR rats in various tests are not indicative of a general increase in "emotionality" or stress level.