A new flavonol from the stem-bark of Premna fulva
A new flavonol from the stem-bark of Premna fulva
复制标题
一种来自Premna fulva 茎皮的新黄酮醇
DOI:
10.3998/ark.5550190.0011.213
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发表时间:
2010-01-01
期刊:
影响因子:
0.9
通讯作者:
Song, Xiao-ping
中科院分区:
文献类型:
--
作者:
Chen, Guang-ying;Dai, Chun-yan;Song, Xiao-ping
A new flavonol, 4'-hydroxy-8,3'- dimethoxy-6-acroleinylflavan-3,4-diol (1) has been isolated from the ethyl acetate extract of stem-bark of Premna fulva Craib, together with six known compounds, vanillic acid(2), syringaresinol(3), naringenin(4), p-hydroxybenzoic acid (5), apigenin (6) and vitexin (7). The structure of 1 was elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HR-ESI-MS, 1D and 2D-NMR. Compounds 1,3,5,6 and 7 were firstly isolated from this plant. To our regret that compound 1 exhibited no activities towards human cancer cell lines HL-60, BGC-823 and Bel-7402 on the bioassay experiments.