Influence of executive function on locomotor function: Divided attention increases gait variability in Alzheimer's disease
Influence of executive function on locomotor function: Divided attention increases gait variability in Alzheimer's disease
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DOI：
10.1046/j.1532-5415.2003.51516.x
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发表时间：
2003-11-01
影响因子：
6.3
通讯作者：
Hausdorff, JM
中科院分区：
文献类型：
--
作者：
Sheridan, PL;Solomont, J;Hausdorff, JM
目的：评价认知功能和注意力分散对阿尔茨海默病（AD）患者步态的影响。设计：以受试者为对照的横断面干预研究。地点：退伍军人事务医疗中心的痴呆患者住院部和门诊部。参与者：28名诊断为疑似AD的患者。干预：认知任务的执行测量：神经心理学测量，包括时钟绘制，言语流畅性，数字广度，获得了沿着临床痴呆评定和简易精神状态检查，痴呆严重程度的措施。步态速度和步幅的步态节律的变化进行了测量，一次在正常行走，一次在双任务walking.RESULTS：在平时的步行，受试者走得很慢，更大的步态变异性比老年人没有AD。步态速度明显降低（P
OBJECTIVES:To evaluate how cognitive function and divided attention affect gait in Alzheimer's disease (AD).DESIGN: Cross-sectional intervention study with subjects serving as their own controls.SETTING: Inpatient unit and outpatient clinic for patients with dementia located at a Veterans Affairs Medical Center.PARTICIPANTS: Twenty-eight patients diagnosed with probable AD.INTERVENTION: Performance of a cognitive task (repeating random digits) while walking.MEASUREMENTS: Neuropsychological measures includ-ing clock drawing, verbal fluency, and digit span were obtained along with the Clinical Dementia Rating and Mini-Mental State Examination, the measures of dementia severity. Gait speed and stride-to-stride variability of gait rhythm were measured, once during normal walking and once during dual-task walking.RESULTS: During usual walking, subjects walked slowly and with greater gait variability than older adults without AD. Gait speed was significantly reduced (P