Epidemiology and Clinical Features of Rocky Mountain Spotted Fever from Enhanced Surveillance, Sonora, Mexico: 2015-2018
Epidemiology and Clinical Features of Rocky Mountain Spotted Fever from Enhanced Surveillance, Sonora, Mexico: 2015-2018
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DOI：
10.4269/ajtmh.20-0854
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发表时间：
2021-01-01
影响因子：
3.3
通讯作者：
Armstrong, Paige A.
中科院分区：
文献类型：
--
作者：
Alvarez-Lopez, Diego, I;Ochoa-Mora, Estefania;Armstrong, Paige A.
落基山斑疹热（RMSF）是由立克次体引起的一种严重的和潜在致命的蜱传疾病。2015年，墨西哥发布了流行病学紧急声明，以应对墨西哥北方正在发生的RMSF疫情。索诺拉州是墨西哥受影响最严重的州之一，历史病死率为18%。我们总结了加强监测的数据，以了解与高死亡率相关的人口统计学、临床和治疗因素。我们对索诺拉健康促进和疾病预防总局报告的确诊和可能的RMSF病例进行了回顾性分析。RMSF病例的定义为发热（> 38.5 ℃），加上两种症状和流行病学标准。确诊病例需要实验室证据。在2015-2018年期间，共报告了510例RMSF病例; 252例（49%）为年龄
Rocky Mountain spotted fever (RMSF), caused by Rickettsia rickettsii, is a severe and potentially fatal tick borne disease. In 2015, Mexico issued a declaration of epidemiologic emergency in response to ongoing outbreaks of RMSF in northern Mexico. Sonora state is one of the most heavily impacted states in Mexico, with historic case fatality rates (CFRs) of 18%. We summarized data from enhanced surveillance to understand demographic, clinical, and treatment factors associated with the high mortality. We conducted a retrospective review of confirmed and probable RMSF cases reported to the General Directorate of Health Promotion and Disease Prevention in Sonora. A case of RMSF is defined as fever (> 38.5 degrees C), plus two symptoms, and epidemiologic criteria. A confirmed case requires laboratory evidence. During 2015-2018, a total of 510 cases of RMSF were reported; 252 (49%) were in persons aged