Synthesis of 5'-C-methyl-1',3'-dioxolan-4'-yl nucleosides.
Synthesis of 5'-C-methyl-1',3'-dioxolan-4'-yl nucleosides.
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5-C-甲基-1,3-二氧戊环-4-基核苷的合成。
DOI：
10.1016/j.bmcl.2003.12.060
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Watanabe,KyoichiA
中科院分区：
文献类型：
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作者：
Du,Jinfa;Patterson,Steven;Shi,Junxing;Chun,Byoung-Kwon;Stuyver,LievenJ;Watanabe,KyoichiA
以外消旋乳酸为原料，合成了2-苯甲酰氧基甲基-4-氧代-5-C-甲基-1，3-二氧戊环，合成了5′-C-甲基-1 ′，3 ′-二氧戊环-4 ′-基核苷。
Novel racemic 5′-C-methyl-1′,3′-dioxolan-4′-yl nucleosides were synthesized from the key intermediate, 2-benzoyloxymethyl-4-oxo-5-C-methyl-1,3-dioxolane, which was prepared from racemic lactic acid.